Rapid access to polyprenylated phloroglucinols via alkylative dearomatization-annulation:: Total synthesis of (±)-clusianone
Rapid access to polyprenylated phloroglucinols via alkylative dearomatization-annulation:: Total synthesis of (±)-clusianone
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DOI：
10.1021/ja0762339
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发表时间：
2007-10-24
影响因子：
15
通讯作者：
Porco, John A., Jr.
中科院分区：
文献类型：
--
作者：
Qi, Ji;Porco, John A., Jr.
一个简明的方法，双环[3.3.1]壬烷框架的聚异戊二烯化间苯三酚天然产物利用串联烷基化脱芳构化成环序列进行说明。使用所开发的方法已经实现了（+/-）-clusianone和复杂金刚烷框架的合成。
A concise approach to the bicyclo[3.3.1]nonane framework of the polyprenylated phloroglucinol natural products utilizing a tandem alkylative dearomatization-annulation sequence is described. Syntheses of (+/-)-clusianone and a complex adamantane framework have been achieved using the developed methodology.