Health Communication and Decision Making about Vaccine Clinical Trials during a Pandemic.

Health Communication and Decision Making about Vaccine Clinical Trials during a Pandemic.
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大流行期间疫苗临床试验的健康沟通和决策。

DOI:
10.1080/10810730.2020.1864520
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发表时间:
2020-10-02
影响因子:
4.4
通讯作者:
Langford AT
Langford AT
中科院分区:
医学3区
文献类型:
--
作者:
Langford AT

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新冠肺炎的大流行放大了临床试验的重要性,以寻找安全有效的疫苗来预防引起新冠肺炎的严重急性呼吸综合征冠状病毒2型。尽管有关疫苗的沟通和疫苗迟疑早在新冠肺炎之前就是挑战,但大流行的双重事实以及健康信息、错误信息和虚假信息的“信息性”为疫苗相关的沟通和决策提出了新的挑战。这篇评论的目的是强调改善考虑参与新冠肺炎疫苗临床试验的成年人的沟通和决策的策略。首先,我提出了一个临床试验参与的一般概念模型,该模型可以应用于各种疫苗和其他临床试验环境。接下来,我介绍了提高疫苗临床试验招募的公平性、包容性和效率的询问(假设、寻求、了解)方法:(1)假设所有患者都想知道他们的选择,(2)寻求利益相关者的建议,(3)知道你的数字。这篇评论中提出的想法旨在加强疫苗特定临床试验的沟通、决策和识字,同时提供可能有助于减少疫苗迟疑和随着时间的推移增加疫苗接种率的战略和资源。
The COVID-19 pandemic has magnified the importance of clinical trials for finding a safe and effective vaccine to protect against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19. Although communication about vaccines and vaccine hesitancy were challenges long before COVID-19, the twin facts of a pandemic and an “infodemic” of health information, misinformation, and disinformation have raised new challenges for vaccine-related communication and decision making. The goal of this commentary is to highlight strategies to improve communication and decision making for adults considering participation in COVID-19 vaccine clinical trials. First, I present a general conceptual model for clinical trial participation that can be applied to various vaccine and other clinical trial contexts. Next, I introduce the ASK (Assume, Seek, Know) approach for enhancing equity, inclusion, and efficiency for vaccine clinical trial recruitment: (1) assume that all patients will want to know their options, (2) seek the counsel of stakeholders, and (3) know your numbers. The ideas presented in this commentary are intended to enhance vaccine-specific clinical trial communication, decision making, and literacy, while dually offering strategies and resources that may help reduce vaccine hesitancy and increase vaccine uptake over time.
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