BIOVERSE: enhancements to the framework for structural, functional and contextual modeling of proteins and proteomes.

BIOVERSE: enhancements to the framework for structural, functional and contextual modeling of proteins and proteomes.
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生物视频:增强蛋白质和蛋白质组结构,功能和上下文建模框架的增强。

DOI:
10.1093/nar/gki401
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发表时间:
2005-07-01
影响因子:
14.9
通讯作者:
Samudrala, R
Samudrala, R
中科院分区:
生物学2区
文献类型:
--
作者:
McDermott, J;Guerquin, M;Frazier, Z;Chang, AN;Samudrala, R

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我们对之前描述的Bioverse Web服务器和计算生物学框架进行了大量增强()。在本次更新中,我们提供了可用的新功能的概述,包括:(i)扩大Bioverse中代表的生物体数量,增加新的数据源和其他地方没有的新预测技术,包括基于网络的注释;(ii)重新设计数据库后端和支持代码,从而显着提高速度,搜索和易用性;以及(iii)创建有状态的和动态的web应用前端以提高界面速度和可用性。集成的基于Java的应用程序还允许动态可视化的真实的和预测的蛋白质相互作用网络。
We have made a number of enhancements to the previously described Bioverse web server and computational biology framework (). In this update, we provide an overview of the new features available that include: (i) expansion of the number of organisms represented in the Bioverse and addition of new data sources and novel prediction techniques not available elsewhere, including network-based annotation; (ii) reengineering the database backend and supporting code resulting in significant speed, search and ease-of use improvements; and (iii) creation of a stateful and dynamic web application frontend to improve interface speed and usability. Integrated Java-based applications also allow dynamic visualization of real and predicted protein interaction networks.
DOI: 10.1038/nbt825
发表时间: 2003-06-01
影响因子: 46.9
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影响因子: 46.9
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期刊: BIOINFORMATICS
影响因子: 5.8
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