Bioinspired Fibers Follow the Track of Natural Spider Silk
Bioinspired Fibers Follow the Track of Natural Spider Silk
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DOI：
10.1021/ma102291m
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发表时间：
2011-03-08
期刊：
影响因子：
5.5
通讯作者：
Perez-Rigueiro, J.
中科院分区：
文献类型：
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作者：
Elices, M.;Guinea, G. V.;Perez-Rigueiro, J.
对重组蜘蛛蛋白溶液纺制的仿生纤维的力学行为和微观结构进行了广泛的表征，并与天然蜘蛛丝进行了比较。纤维。已证实，通过基因工程和常规纺丝技术可以生产出与天然蜘蛛丝几乎无法区分的高性能仿生纤维，甚至可以生产出大尺寸的纤维。研究还发现，由含有不同序列基序的类蜘蛛蛋白纺制的纤维在结晶度和链排列方面表现出不同的微观结构，但这些差异并未反映在不同的拉伸性能上。这种机械行为上的相似性表明，生物启发纤维在很大程度上独立于它们重组蛋白质的确切序列，特别是它们的脯氨酸含量。最后，结果表明，天然纤维和生物启发纤维之间的最大差异出现在非常大的变形处，这标志着仿丝纤维的合成面临着终极挑战。
The mechanical behavior and microstructure of bioinspired fibers spun from solutions of recombinant spidroin-like proteins were extensively characterized, and compared with those of natural spider silk. fibers. It is confirmed that high performance bioinspired fibers indistinguishable from natural spider silk up to large strains can be produced through genetic engineering and conventional spinning technologies. It is also found that fibers spun from spidroin-like proteins that contain different motifs of sequence exhibit variations in their microstructure in terms of crystallinity and chain alignment, but these differences are not reflected in distinct tensile properties. This similarity in terms of their mechanical behavior indicates that bioinspired fibers are largely independent of their exact sequence of recombinant proteins and, in particular, of their proline content. Finally, it is shown that the largest differences between natural and bioinspired fibers are found at very large deformations, marking the ultimate challenge in the synthesis of silk-like fibers.