Transperineal prostate biopsy: analysis of a uniform core sampling pattern that yields data on tumor volume limits in negative biopsies.

Transperineal prostate biopsy: analysis of a uniform core sampling pattern that yields data on tumor volume limits in negative biopsies.
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DOI:
10.1186/1742-4682-7-23
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发表时间:
2010-06-17
影响因子:
--
通讯作者:
Kepner JV
Kepner JV
中科院分区:
生物学4区
文献类型:
--
作者:
Kepner GR;Kepner JV

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分析一种分配经会阴前列腺活检核心的方法,该方法可生成活检阴性时可能存在的肿瘤体积数据,并提高检测效率。采用采样和概率论的基本原理来分析经会阴活检模式,该模式使用均匀间隔的平行核心,以提取可能存在的小球形肿瘤体积的定量数据,即使活检未检测到它,即阴性活检。这种分配活检核心的方法提供了可能存在的小球形肿瘤体积上限的数据,以及当活检呈阴性时较小体积的概率,并为评估不同核心间距的有效性提供了定量基础。均匀分布经会阴活检芯提供了一种计算活检阴性时存在给定体积肿瘤的概率的方法,并且可以提高检测效率。
Analyze an approach to distributing transperineal prostate biopsy cores that yields data on the volume of a tumor that might be present when the biopsy is negative, and also increases detection efficiency. Basic principles of sampling and probability theory are employed to analyze a transperineal biopsy pattern that uses evenly-spaced parallel cores in order to extract quantitative data on the volume of a small spherical tumor that could potentially be present, even though the biopsy did not detect it, i.e., negative biopsy. This approach to distributing biopsy cores provides data for the upper limit on the volume of a small, spherical tumor that might be present, and the probability of smaller volumes, when biopsies are negative and provides a quantitative basis for evaluating the effectiveness of different core spacing distances. Distributing transperineal biopsy cores so they are evenly spaced provides a means to calculate the probability that a tumor of given volume could be present when the biopsy is negative, and can improve detection efficiency.
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