Plugging it in: signaling circuits and the yeast cell cycle.
Plugging it in: signaling circuits and the yeast cell cycle.
复制标题
将其插入：信号电路和酵母细胞周期。
DOI：
10.1016/s0955-0674(96)80069-x
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发表时间：
1996
影响因子：
7.5
通讯作者：
Reed,SI
中科院分区：
文献类型：
--
作者：
Wittenberg,C;Reed,SI
信号转导途径提供了传递信息和引起特异性反应的手段。细胞周期机制的调节就是这样一种反应。芽殖酵母的分子遗传学方法有助于阐明这些复杂信号通路的组成部分以及这些组成部分之间的相互关系。最近的进展揭示了细胞外信号与细胞周期进程和形态发生机制之间的联系。营养和检查点信号与细胞周期装置之间的界面的性质刚刚出现。
Signal transduction pathways provide the means to transmit information and elicit specific responses. Modulation of the cell cycle machinery is one such response. Molecular genetic approaches with budding yeast have been instrumental in elucidating the components of these complex signaling pathways and the inter-relationships among these components. Recent progress has revealed pathways that link extracellular signals with the machinery governing both cell cycle progression and morphogenesis. The nature of the interface between nutritional and checkpoint signals with the cell cycle apparatus is just now emerging.