Nonlinear effects in optical trapping of titanium dioxide and diamond nanoparticles.
Nonlinear effects in optical trapping of titanium dioxide and diamond nanoparticles.
复制标题
二氧化钛和金刚石纳米颗粒光学捕获的非线性效应。
DOI：
10.1016/j.bpj.2023.07.018
复制
发表时间：
2023
影响因子：
3.4
通讯作者：
Woodside,MichaelT
中科院分区：
文献类型：
--
作者：
Devi,Anita;Neupane,Krishna;Jung,Haksung;Neuman,KeirC;Woodside,MichaelT
Optical trapping in biophysics typically uses micron-scale beads made of materials like polystyrene or glass to probe the target of interest. Using smaller beads made of higher-index materials could increase the time resolution of these measurements. We characterized the trapping of nanoscale beads made of diamond and titanium dioxide (TiO2) in a single-beam gradient trap. Calculating theoretical expectations for the trapping stiffness of these beads, we found good agreement with measured values. Trap stiffness was significantly higher for TiO2beads, owing to notable enhancement from nonlinear optical effects, not previously observed for continuous-wave trapping. Trap stiffness was over 6-fold higher for TiO2beads than polystyrene beads of similar size at 70 mW laser power. These results suggest that diamond and TiO2nanobeads can be used to improve time resolution in optical tweezers measurements.
