Effects of Merino Wool on Atopic Dermatitis Using Clinical, Quality of Life, and Physiological Outcome Measures
Effects of Merino Wool on Atopic Dermatitis Using Clinical, Quality of Life, and Physiological Outcome Measures
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DOI：
10.1097/der.0000000000000449
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发表时间：
2019-05-01
期刊：
影响因子：
5.2
通讯作者：
Lorenz, Douglas
中科院分区：
文献类型：
--
作者：
Fowler, Joseph F., Jr.;Fowler, Lynn M.;Lorenz, Douglas
背景：对于患有敏感性皮肤或特应性皮炎的人来说，羊毛服装可能被认为是一个糟糕的选择。目的本研究的目的是评价穿着细美利奴羊毛服装与标准服装对特应性皮炎的影响，并评估美利奴羊毛服装对5岁及以上特应性皮炎儿童和成人生活质量的影响。方法对轻度至中度特应性皮炎受试者在穿美利奴羊毛服装6周和穿标准服装6周后交叉评估湿疹面积和严重程度指数、皮肤病生活质量指数、静态研究者总体评估和皮肤水合作用。结果穿着美利奴羊毛服装时，与标准服装相比，平均湿疹面积和严重程度指数评分、皮肤病生活质量指数评分和静态研究者总体评估评分均出现统计学显著改善。皮肤水合作用无显著差异。与穿着标准服装相比，穿着美利奴羊毛服装不会对皮肤产生任何负面影响。结论：与标准服装相比，美利奴羊毛服装可改善特应性皮炎的严重程度以及特应性患者的生活质量。
Background Wool clothing may be perceived as a poor choice for use by individuals with sensitive skin or atopic dermatitis. Objectives The aims of the study were to evaluate the effect on atopic dermatitis of wearing fine Merino wool clothing versus standard clothing and to assess the effect of Merino wool clothing on quality of life in children and adults with atopic dermatitis 5 years and older. Methods Subjects with mild to moderate atopic dermatitis were assessed in a crossover fashion after wearing Merino wool clothing for 6 weeks and standard clothing for 6 weeks, for Eczema Area and Severity Index, Dermatology Life Quality Index, static Investigator's Global Assessment, and skin hydration. Results While wearing Merino wool clothing, compared with standard clothing, statistically significant improvements were seen in mean Eczema Area and Severity Index scores, Dermatology Life Quality Index scores, and static Investigator's Global Assessment scores. No significant difference was seen with skin hydration. Wearing Merino wool clothing did not produce any negative cutaneous effects compared with wearing standard clothing. Conclusions Merino wool clothing compared with standard clothing provided improvements in severity of atopic dermatitis as well as quality of life in atopic patients.