CT time-attenuation washout curves of adrenal adenomas and nonadenomas
CT time-attenuation washout curves of adrenal adenomas and nonadenomas
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DOI：
10.2214/ajr.170.3.9490968
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发表时间：
1998-03-01
影响因子：
5
通讯作者：
Londy, F
中科院分区：
文献类型：
--
作者：
Korobkin, M;Brodeur, FJ;Londy, F
目标。本研究的目的是分析肾上腺肿块的CT增强冲洗曲线，并确定初始增强后腺瘤与非腺瘤区分的最早时间。材料和方法。对52例肾上腺腺瘤和24例非肾上腺腺瘤进行延迟CT增强扫描，生成对比增强冲洗曲线。根据衰减值确定诊断腺瘤的最佳阈值及相应的敏感性和特异性。此外，我们计算了初始增强后5至45分钟增强冲洗时间延迟的百分比和相对百分比。肾上腺腺瘤在5分钟和15分钟增强洗脱的平均百分比分别为51%和70%，而非腺瘤分别为8%和20%。15 min延迟增强扫描阈值衰减为37 H时，诊断腺瘤的敏感性和特异性均为96%。在CT上，肾上腺腺瘤比非腺瘤表现出更早和更快的增强扫描消失。早在增强后5- 15min，可通过衰减值或洗脱百分比或相对百分比来区分腺瘤和非腺瘤。
OBJECTIVE. The purpose of this study was to analyze the CT contrast enhancement washout curves of adrenal masses and to determine the earliest time after initial enhancement that differentiation of adenomas from nonadenomas is possible.MATERIALS AND METHODS. Contrast enhancement washout curves were generated after delayed contrast-enhanced CT scans of 52 adrenal adenomas and 24 nonadenomas. The optimal threshold value and corresponding sensitivity and specificity for the diagnosis of adenoma were determined according to attenuation values. Also, we calculated the percentage and relative percentage of enhancement washout al time delays from 5 to 45 min after initial enhancement.RESULTS. The mean percentage of enhancement washout for adrenal adenomas was 51% at 5 min and 70% at 15 min, compared with 8% and 20%, respectively, for nonadenomas. The sensitivity and specificity for the diagnosis of adenoma were both 96% at a threshold attenuation value of 37 H on the 15-min delayed enhanced scan.CONCLUSION. On CT, adrenal adenomas show a much earlier and more rapid washout of contrast enhancement than do nonadenomas. Adenomas and nonadenomas can be differentiated by attenuation values or the percentage or relative percentage of washout as early as 5-15 min after enhancement.