Predictive value of a history of varicella infection.
Predictive value of a history of varicella infection.
复制标题
水痘感染史的预测价值。
DOI：
--
复制
发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Candice N Holmes
中科院分区：
文献类型：
--
作者：
Candice N Holmes
目的
确定既往水痘感染史是否是既往感染的可靠标志。
证据质量
使用MeSH标题“水痘”、“水痘”和“病史采集”检索MEDLINE，时间为1996年1月至2002年5月。“本文的建议是基于精心设计的横断面研究的证据。
主要信息
对于那些水痘阴性或不确定病史的人，建议进行血清学检测，而不是假定的疫苗接种;大多数人都有免疫力。对于那些有水痘阳性史的人，给出的建议取决于人口。对于水痘感染风险较高的人群（如医护人员、孕妇），建议进行常规血清检测。对于低风险人群，医生可以接受水痘阳性史作为免疫力的可靠指标。
结论
大多数研究发现，患者的水痘病史具有较高的阳性预测值和较低的阴性预测值。这些发现表明，水痘阳性史是疾病的可靠标志，而阴性史并不能预测缺乏免疫力。
OBJECTIVE
To determine whether a history of previous varicella infection provides a reliable marker for prior infection.
QUALITY OF EVIDENCE
MEDLINE was searched from January 1996 to May 2002 using the MeSH headings "varicella," "chickenpox" and "medical history taking." Recommendations in this paper are based on evidence from well designed cross-sectional studies.
MAIN MESSAGE
Serologic testing is advised, rather than presumptive vaccination, for those with a negative or uncertain history of varicella; most will be immune. For those with a positive history of varicella, the advice given depends on the population. For populations at higher risk of varicella infection (eg, health care workers, pregnant women), routine serum testing is recommended. For low-risk populations, physicians could accept a positive history of varicella as a reliable indicator of immunity.
CONCLUSION
Most studies found that patients' history of varicella had a high positive predictive value and a low negative predictive value. These findings suggest that a positive history of varicella is a reliable marker of disease while a negative history does not not predict lack of immunity.