LOCALIZATION OF ALPHA-TUBULIN IMMUNOREACTIVITY TO CEREBELLAR BERGMANN GLIA WITH THE TU-01 ANTIBODY

LOCALIZATION OF ALPHA-TUBULIN IMMUNOREACTIVITY TO CEREBELLAR BERGMANN GLIA WITH THE TU-01 ANTIBODY
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DOI:
10.1007/bf00495643
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发表时间:
1984-01-01
期刊:
HISTOCHEMISTRY
影响因子:
--
通讯作者:
ROSTOMIAN, MA
ROSTOMIAN, MA
中科院分区:
其他
文献类型:
--
作者:
HAJOS, F;ROSTOMIAN, MA

文献摘要

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特异于α-微管蛋白的TU 01抗微管蛋白抗体光镜和电镜免疫细胞化学显示微管蛋白对大鼠小脑Bergmann胶质细胞有选择性染色。在神经胶质细胞及其纤维内,微管、滑面内质网、线粒体外膜和胞体的核糖体突起被抗体修饰。这种抗体的高选择性讨论微管蛋白的微观异质性。
The TU 01 antitubulin antibody specific for .alpha.-tubulin was demonstrated by light microscopic and EM immunocytochemistry to stain selectively the Bergmann glia of rat cerebellum. Within the glial cells and their fibers, the microtubules, the smooth endoplasmic reticulum, the outer mitochondrial membranes and the ribosomal rosettes of the cell body were decorated by the antibody. The high selectivity of this antibody is discussed in terms of tubulin microheterogeneity.