Diagnostic value of chest computed tomography imaging for COVID-19 based on reverse transcription-polymerase chain reaction: a meta-analysis.
Diagnostic value of chest computed tomography imaging for COVID-19 based on reverse transcription-polymerase chain reaction: a meta-analysis.
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基于逆转录聚合酶链反应的胸部计算机断层扫描成像对COVID-19的诊断价值：荟萃分析
DOI：
10.1186/s40249-021-00910-8
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发表时间：
2021-10-21
影响因子：
8.1
通讯作者：
Li H
中科院分区：
文献类型：
--
作者：
Liu J;Yang X;Zhu Y;Zhu Y;Liu J;Zeng X;Li H
背景新冠肺炎的CT诊断价值存在争议。方法检索并收集多个文献平台上有关胸部CT对新冠肺炎诊断价值的中英文文献。对研究的质量评估和偏倚风险进行了评估。进行异质性检验和荟萃分析，包括标绘敏感度(SEN)、特异度(SPE)、合并阳性似然比(+LR)、阴性似然比(-LR)、诊断优势比(DOR)和95%可信区间(CI)。如果存在阈值效应，则进一步绘制概要接收器工作特征曲线(SROC)。计算受试者工作特征曲线下的汇集面积(AUROC)和95%CI。结果对所有文献进行评价后，纳入20篇诊断性研究，共计9004例患者。异质性的原因是阈值效应造成的，因此新冠肺炎胸部CT的AUROC = 为0.91(95%CI：0.89~0.94)。2 0项研究的合并敏感度、特异度、 +LR、-LR分别为0.91(95%CI：0.88~0.94)、0.71(95%CI：0.5 9~0.80)、3.1(95%CI：2.2~4.4)、0.12(95%CI：0.0 9~0.17)。经q检验，I2为85.6%(P= 0.001)。结论本研究结果显示，新冠肺炎的CT诊断接近参考标准。如果有一个统一的新冠肺炎诊断标准，胸部CT的诊断价值可能会进一步提高。不过，请注意合理使用CT.图表摘要
BackgroundThe computed tomography (CT) diagnostic value of COVID-19 is controversial. We summarized the value of chest CT in the diagnosis of COVID-19 through a meta-analysis based on the reference standard.MethodsAll Chinese and English studies related to the diagnostic value of CT for COVID-19 across multiple publication platforms, was searched for and collected. Studies quality evaluation and plotting the risk of bias were estimated. A heterogeneity test and meta-analysis, including plotting sensitivity (Sen), specificity (Spe) forest plots, pooled positive likelihood ratio (+LR), negative likelihood ratio (-LR), dignostic odds ratio (DOR) values and 95% confidence interval (CI), were estimated. If there was a threshold effect, summary receiver operating characteristic curves (SROC) was further plotted. Pooled area under the receiver operating characteristic curve (AUROC) and 95%CIwere also calculated.ResultsTwenty diagnostic studies that represented a total of 9004 patients were included from 20 pieces of literatures after assessing all the aggregated studies. The reason for heterogeneity was caused by the threshold effect, so the AUROC = 0.91 (95%CI: 0.89–0.94) for chest CT of COVID-19. Pooled sensitivity, specificity, +LR, -LR from 20 studies were 0.91 (95%CI:0.88–0.94), 0.71 (95%CI: 0.59–0.80), 3.1(95%CI:2.2–4.4), 0.12 (95%CI:0.09–0.17), separately. TheI2was 85.6% (P= 0.001) by Q-test.ConclusionsThe results of this study showed that CT diagnosis of COVID-19 was close to the reference standard. The diagnostic value of chest CT may be further enhanced if there is a unified COVID-19 diagnostic standard. However, please pay attention to rational use of CT.Graphic Abstract
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DOI：
10.4103/lungindia.lungindia_410_20
发表时间：
2021-03
期刊：
Lung India : official organ of Indian Chest Society
影响因子：
--
作者：
Ravikanth R
通讯作者：
Ravikanth R
影响因子：
5.9
作者：
Booij R;Budde RPJ;Dijkshoorn ML;van Straten M
通讯作者：
van Straten M
DOI：
10.1016/j.bjid.2020.10.002
发表时间：
2020-11
期刊：
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
影响因子：
--
作者：
Grando RD;Brentano VB;Zanardo AP;Hertz FT;Júnior LCA;Prietto Dos Santos JF;Galvão GS;Zavascki AP;Gazzana MB
通讯作者：
Gazzana MB
影响因子：
19.7
作者：
Caruso, Damiano;Zerunian, Marta;Laghi, Andrea
通讯作者：
Laghi, Andrea
影响因子：
3.3
作者：
Falaschi, Zeno;Danna, Pietro S. C.;Carriero, Alessandro
通讯作者：
Carriero, Alessandro