Treatment of the primary hyperoxalurias: a new chapter.

Treatment of the primary hyperoxalurias: a new chapter.
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DOI:
10.1038/sj.ki.5001821
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发表时间:
2006-10
影响因子:
19.6
通讯作者:
D. Milliner
D. Milliner
中科院分区:
医学1区
文献类型:
--
作者:
D. Milliner

文献摘要

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尽管原发性高草酸尿症的酶学、分子遗传学和临床知识取得了进展,但可用的治疗方法很少。草酸杆菌形成是一种有前途的新疗法,有可能诱导草酸盐分泌到肠腔中,并在肠腔中被细菌降解。
Despite advances in the enzymology, molecular genetics, and clinical knowledge of the primary hyperoxalurias, few treatments are available.Oxalobacter formigenesis a promising new therapy with potential to induce secretion of oxalate into the intestinal lumen, where it can be degraded by the bacteria.