Surrogate spike train generation through dithering in operational time
Surrogate spike train generation through dithering in operational time
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DOI：
10.3389/fncom.2010.00127
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发表时间：
2010-09-01
影响因子：
3.2
通讯作者：
Diesmann, Markus
中科院分区：
文献类型：
--
作者：
Louis, Sebastien;Gerstein, George L.;Diesmann, Markus
对于许多类型的锋电位序列，检测锋电位同步的过度并检验其显著性不能通过分析来完成，而依赖于适当的替代方法。这些方法的主要挑战是保存尖峰序列的某些特征，其中两个最重要的特征是放电率和尖峰间隔统计。在本研究中，我们利用操作时间对尖峰抖动进行概括，并提出了两种新型的替代方法，可以高准确度地保留这两个特征。与早期的方法相比，该方法在检测尖峰序列之间的过度同步方面显示出改进的鲁棒性。
Detecting the excess of spike synchrony and testing its significance can not be done analytically for many types of spike trains and relies on adequate surrogate methods. The main challenge for these methods is to conserve certain features of the spike trains, the two most important being the firing rate and the inter-spike interval statistics. In this study we make use of operational time to introduce generalizations to spike dithering and propose two novel surrogate methods which conserve both features with high accuracy. Compared to earlier approaches, the methods show an improved robustness in detecting excess synchrony between spike trains.