THE INVOLVEMENT OF THE ANTERIOR CINGULATE CORTEX IN BLOOD-PRESSURE CONTROL
THE INVOLVEMENT OF THE ANTERIOR CINGULATE CORTEX IN BLOOD-PRESSURE CONTROL
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DOI：
10.1016/0006-8993(85)90774-7
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发表时间：
1985-01-01
期刊：
影响因子：
2.9
通讯作者：
WYSS, JM
中科院分区：
文献类型：
--
作者：
BURNS, SM;WYSS, JM
通过电刺激麻醉和清醒动物的前扣带皮层，研究了该区域的内脏运动特性。最初的研究表明，电刺激前扣带皮层的任何分支都能引起戊巴比妥钠麻醉大鼠血压的显著下降。在刺激前扣带皮层腹侧第3区后，降压反应最大（最多减少50%）。扣带皮层刺激没有改变心率。在清醒的动物中，刺激前扣带皮层吻侧三分之一的先前确定的抑制位点引发了压力反应。相反，刺激这一皮层的尾侧三分之一会引发抑郁反应，而刺激中间三分之一会引发双相反应（升压后是降压）。前扣带皮层是一个内脏运动区，它可能为与学习和/或压力相关的血压反应的调节提供皮质输出。
The visceromotor nature of the rat anterior cingulate cortex was investigated by electrically stimulating this area in both anesthetizes and awake animals. Initial studies demonstrated that electrical stimulation of any division of the anterior cingulate cortex elicits a significant fall in blood pressure in the sodium pentobarbital-anesthetized rat. Depressor responses were greatest (up to 50% decreases) following stimulation of the ventral 3rd of the anterior cingulate cortex. Heart rate was not altered by cingulate cortex stimulation. In the awake animal, stimulation of previously identified depressor sites in the rostral third of the pregenual cingulate cortex elicited pressor responses. In contrast, stimulation of the caudal 3rd of this cortex elicited depressor responses, and stimulation of the middle 3rd elicited biphasic (pressor followed by depressor) responses. The anterior cingulate cortex is a visceromotor region which may provide a cortical output for the regulation of blood pressure responses associated with learning and or stress.