Varicella-zoster virus in the saliva of patients with herpes zoster
Varicella-zoster virus in the saliva of patients with herpes zoster
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DOI：
10.1086/527420
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发表时间：
2008-03-01
影响因子：
6.4
通讯作者：
Pierson, Duane L.
中科院分区：
文献类型：
--
作者：
Mehta, Satish K.;Tyring, Stephen K.;Pierson, Duane L.
54 名带状疱疹患者接受伐昔洛韦治疗。在治疗第 1、8 和 15 天，对疼痛进行评分并检查唾液中的水痘带状疱疹病毒 (VZV) DNA。每名患者在治疗开始当天就发现了 VZV DNA，82% 的患者随后消失了。 VZV DNA 的存在与疼痛之间以及 VZV DNA 拷贝数与疼痛之间呈正相关（P
Fifty-four patients with herpes zoster were treated with valacyclovir. On treatment days 1, 8, and 15, pain was scored and saliva examined for varicella-zoster virus (VZV) DNA. VZV DNA was found in every patient the day treatment was started and later disappeared in 82%. There was a positive correlation between the presence of VZV DNA and pain and between VZV DNA copy number and pain (P