CORONAVIRUS INFECTION OF THE BOVINE RESPIRATORY-TRACT
CORONAVIRUS INFECTION OF THE BOVINE RESPIRATORY-TRACT
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DOI：
10.1016/0378-1135(84)90063-4
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发表时间：
1984-01-01
影响因子：
3.3
通讯作者：
LOGAN, EF
中科院分区：
文献类型：
--
作者：
MCNULTY, MS;BRYSON, DG;LOGAN, EF
从患有呼吸道疾病的小牛的肺和气管培养的牛气管器官中分离出两种病毒，它们在形态上与冠状病毒相似，在抗原性上与牛肠道冠状病毒难以区分。将这些病毒经鼻和气管内接种到新生小牛体内，主要导致上呼吸道感染，这与轻度呼吸道症状的发展有关。
Two viruses, morphologically resembling coronaviruses and antigenically indistinguishable from bovine enteric coronavirus, were isolated in bovine tracheal organ cultures from the lungs and trachea of young calves with respiratory disease. Intranasal and intratracheal inoculation of these viruses into neonatal calves resulted in a predominantly upper respiratory tract infection, which was associated with the development of mild respiratory symptoms.