RECURRENT ASPIRATION IN CHILDREN - LIPID-LADEN ALVEOLAR MACROPHAGE QUANTITATION
RECURRENT ASPIRATION IN CHILDREN - LIPID-LADEN ALVEOLAR MACROPHAGE QUANTITATION
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DOI：
10.1002/ppul.1950030209
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发表时间：
1987-03-01
影响因子：
3.1
通讯作者：
HALLBERG, TK
中科院分区：
文献类型：
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作者：
COLOMBO, JL;HALLBERG, TK
我们前瞻性评价了45例年龄为1个月至25岁（平均3.3岁）的患者的支气管冲洗液中是否存在载脂巨噬细胞。通过对细胞内油红O阳性物质的量进行分级，我们确定了每例患者的半定量载脂巨噬细胞指数。所有观察到的明确抽吸者（n = 22）的指数均≥ 86（平均值± SD，139 ± 46）。所有临床上无误吸嫌疑的患者（n = 23）的指数均> 72（平均值± SD，21 ± 20）。我们的研究结果表明，简单地看到充满脂质的巨噬细胞是一种非特异性的发现，但这些细胞的定量可能是儿童反复吸入食物物质的一个非常好的测试。该试验似乎比放射学检查更敏感。儿科肺学1987; 3：89 - 89。
We prospectively evaluated bronchial washings from 45 patients aged 1 month to 25 years (mean 3.3 years) for the presence of lipid‐laden macrophages. By grading the amount of intracellular oil‐red‐O‐positive material, we determined a semiquantitative lipid‐laden macrophage index for each patient. All patients observed to be definite aspirators (n = 22) had indexes ≥86 (mean ± SD, 139 ± 46). All patients with no clinical suspicion of aspiration (n = 23) had indexes ⩽72 (mean ± SD, 21 ± 20). Our results suggest that simply sighting lipid‐laden macrophages is a nonspecific finding, but quantitation of these cells may be a very good test for recurrent aspiration of food substances in children. This test appears to be more sensitive than radiographic studies.Pediatr Pulmonol 1987; 3:89–89.