Relationship between echocardiographic and cardiac magnetic resonance imaging-derived measures of right ventricular function in patients with chronic thromboembolic pulmonary hypertension

Relationship between echocardiographic and cardiac magnetic resonance imaging-derived measures of right ventricular function in patients with chronic thromboembolic pulmonary hypertension
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慢性血栓栓塞性肺动脉高压患者右心室功能超声心动图和心脏磁共振成像测量之间的关系

DOI:
10.1016/j.thromres.2015.01.008
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发表时间:
2015-04-01
影响因子:
7.5
通讯作者:
Lu, Xiu-zhang
Lu, Xiu-zhang
中科院分区:
医学3区
文献类型:
--
作者:
Li, Yi-dan;Wang, Yi-dan;Lu, Xiu-zhang

文献摘要

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背景:超声心动图广泛用于评价右室功能。然而,超声心动图参数评估慢性血栓栓塞性肺动脉高压(CTEPH)患者右室功能的价值尚不清楚。本研究分析超声心动图参数与心脏磁共振(CMR)测量右室射血分数(RVEF)的相关性,以系统地阐明超声心动图参数在评价CTEPH患者右室功能中的作用。方法:应用超声心动图测量组织多普勒衍生的三尖瓣环侧向收缩速度(S‘)、面积变化分数(FAC)、心肌功能指数(MPI)和三尖瓣环平面收缩期离散度(TAPSE)。结果:S的右室舒张末容量与右室收缩末期容量呈显著正相关(r=0.689,P<TAPSE与右室射血分数无相关性(r=0.0001,P=0.0001)。结论:超声心动图可常规应用于慢性充血性心力衰竭患者的右心功能检测,以评价右心功能。(C)2015爱思唯尔有限公司。保留所有权利。
Background: Echocardiography is widely used to evaluate right ventricular (RV) function. However, the value of echocardiographic parameters to assess RV function in patients with chronic thromboembolic pulmonary hypertension (CTEPH) is unknown. In this study, we analyzed the correlations between echocardiographic parameters and the RV ejection fraction (RVEF) as measured by cardiacmagnetic resonance (CMR) imaging to systematically elucidate the role of echocardiographic parameters in the assessment of RV function in patients with CTEPH.Methods: Echocardiography was used to measure the tissue Doppler- derived tricuspid lateral annular systolic velocity (S'), fractional area change (FAC), myocardial performance index (MPI), and tricuspid annular plane systolic excursion (TAPSE). CMR was used to measure the RV end-diastolic volume (RVEDV) and end-systolic volume (RVESV), and the RVEF was calculated.Results: A significant positive correlation was found between S' and RVEF (r = 0.689, P < 0.0001) and between FAC and RVEF (r = 0.423, P = 0.022), a significant negative correlation was found between MPI and RVEF (r = -0.387, P = 0.048), and no correlation was found between TAPSE and RVEF (r = 0.451, P = 0.22).Conclusion: Echocardiography can be routinely used in the clinical setting to measure S', FAC, and MPI for the evaluation of right heart function in patients with CTEPH. (C) 2015 Elsevier Ltd. All rights reserved.