A computerized analysis of the entire retinal ganglion cell population and its spatial distribution in adult rats
A computerized analysis of the entire retinal ganglion cell population and its spatial distribution in adult rats
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DOI：
10.1016/j.visres.2008.09.029
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发表时间：
2009-01-01
期刊：
影响因子：
1.8
通讯作者：
Vidal-Sanz, M.
中科院分区：
文献类型：
--
作者：
Salinas-Navarro, M.;Mayor-Torroglosa, S.;Vidal-Sanz, M.
在成年白化病（SD）和色素（PVG）大鼠的视网膜神经节细胞（RGC）的整个人口进行了定量，并使用计算机技术分析其空间分布。用荧光金（FG）从视神经（ON）或上级丘（SCi）回标记RGCs。ON标记的RGC数量[SD：82，818 +/-3，949，n = 27; PVG：89，241 +/-3，576，n = 6]与SCi标记的RGC数量[SD：81，486 +/-4，340，n = 37; PVC：87，229 +/-3，199; n = 59]相当。详细的方法，以提供细胞密度的信息，在小尺度上表现出一个水平区域的存在下，在背侧视网膜密度最高，类似于视觉条纹。(C)2008爱思唯尔有限公司保留所有权利。
In adult albino (SD) and pigmented (PVG) rats the entire population of retinal ganglion cells (RGCs) was quantified and their spatial distribution analyzed using a computerized technique. RGCs were back-labelled from the optic nerves (ON) or the superior colliculi (SCi) with Fluorogold (FG). Numbers of RGCs labelled from the ON [SD: 82,818 +/- 3,949, n = 27; PVG: 89,241 +/- 3,576, n = 6) were comparable to those labelled from the SCi [SD: 81,486 +/- 4,340, n = 37; PVC: 87,229 +/- 3,199; n = 59]. Detailed methodology to provide cell density information at small scales demonstrated the presence of a horizontal region in the dorsal retina with highest densities, resembling a visual streak. (C) 2008 Elsevier Ltd. All rights reserved.