Antioxidant activities of curcumin, demethoxycurcumin and bisdemethoxycurcumin
Antioxidant activities of curcumin, demethoxycurcumin and bisdemethoxycurcumin
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DOI：
10.1016/j.foodchem.2005.06.037
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发表时间：
2006-01-01
期刊：
影响因子：
8.8
通讯作者：
Sakariah, KK
中科院分区：
文献类型：
--
作者：
Jayaprakasha, GK;Rao, LJ;Sakariah, KK
消费者现在越来越意识到与饮食相关的健康问题，因此需要安全且促进健康的天然成分。最近，许多关于姜黄素对健康益处的研究已经被报道。在本研究中，尝试通过体外模型系统（例如磷钼和亚油酸过氧化方法）测试单个姜黄素（例如姜黄素、双去甲氧基姜黄素和去甲氧基姜黄素）的抗氧化活性。提取物的抗氧化能力，以抗坏血酸当量（μmol/g）计，顺序为：姜黄素>去甲氧基姜黄素>双去甲氧基姜黄素。与丁基羟基甲苯 (BHT) 相比，在 100 ppm 时，姜黄素通过亚油酸过氧化产生的抗氧化活性最高，其次是去甲氧基姜黄素和双去甲氧基姜黄素。体外模型获得的数据清楚地确定了单个姜黄素的抗氧化效力。这是首次利用磷钼法和亚油酸过氧化法研究单个姜黄素类抗氧化活性。 (c) 2005 Elsevier Ltd. 保留所有权利。
Consumers are now increasingly aware of diet-related health problems and therefore, demanding natural ingredients which are expected to be safe and health-promoting. Recently, many studies on health benefits associated with curcumin have been reported. In the present study, an attempt has been made to test individual curcuminoids, such as curcumin, bisdemethoxycurcumin and demethoxycurcumin, for their antioxidant activities by in vitro model systems, such as the phosphomolybdenum and linoleic acid peroxidation methods. Antioxidant capacities of the extracts, as ascorbic acid equivalent (mu mol/g) were in the order: curcumin > demethoxycurcumin > bisdemethoxycurcumin. In comparison with butylated hydroxyl toluene (BHT), at 100 ppm, the antioxidant activity, by linoleic acid peroxidation, was found to be highest with curcumin, followed by demethoxycurcumin and bisdemethoxycurcumin. The data obtained by the in vitro models clearly establish the antioxidant potencies of individual curcuminoids. This is the first report on antioxidant activity of individual curcuminoids using the phosphomolybdenum method and linoleic acid peroxidation method. (c) 2005 Elsevier Ltd. All rights reserved.