Correction of motion-induced misalignment in co-registered PET/CT and MRI (T1/T2/FLAIR) head images for stereotactic radiosurgery.
Correction of motion-induced misalignment in co-registered PET/CT and MRI (T1/T2/FLAIR) head images for stereotactic radiosurgery.
复制标题
纠正立体定向放射外科联合配准 PET/CT 和 MRI (T1/T2/FLAIR) 头部图像中运动引起的错位。
DOI：
10.1120/jacmp.v12i1.3306
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Miller,RobertW
中科院分区：
文献类型：
--
作者：
Li,Guang;Xie,Huchen;Ning,Holly;Citrin,Deborah;Kaushal,Aradhana;Camphausen,Kevin;Miller,RobertW
目的是评估和纠正使用三维体积图像配准（3DVIR）对立体定向放射外科（SRS）诊断性PET/CT和MRI/MRI图像的共配准。3DVIR利用体积解剖地标上颜色分布的均匀性作为亚毫米精度的配准标准。采用常见的头部固定器，通过混合PET/CT或MRI扫描仪依次获得53组脑病变患者的PET/CT和MRI （T1， T2和FLAIR）图像集。在10分钟的间隔内扫描25组头部图像，在30分钟的间隔内扫描14组全身图像。获得14组MRI图像，并在时间0和分钟顺序扫描每个3模态图像集（T1， T2和FLAIR）。使用3DVIR评估和纠正这些“共配”图像中的错位。使用诊断性PET/CT和MRI/MRI成像中常见的头部固定装置，80%-100%的这些“共注册”图像被识别为错位。对于PET/CT， 10分钟扫描时的偏差大小为和，30分钟扫描时的偏差大小为和。对于MRI/MRI， 5分钟扫描间隔的幅度为和，20分钟扫描间隔的幅度为和。在诊断性PET/CT和MRI/MRI图像共配准中存在微小但显著的不对中，可以在SRS治疗计划中使用体积图像配准来纠正，以提高临床容错范围内的目标定位。PACS数字：87.53。Ly, 87.57。新泽西,87.57。英国,87.57。问量,87.61。jc, 87.19。利益冲突声明：作者在本研究报告中没有任何利益冲突。
The purpose was to evaluate and correct the co‐registration of diagnostic PET/CT and MRI/MRI images for stereotactic radiosurgery (SRS) using 3D volumetric image registration (3DVIR). The 3DVIR utilizes the homogeneity of color distribution over a volumetric anatomical landmark as the registration criterion with submillimeter accuracy. Fifty‐three PET/CT and MRI (T1, T2 and FLAIR) image sets of patients with brain lesions were acquired sequentially from a hybrid PET/CT or an MRI scanner with common diagnostic head holding devices. Twenty‐five sets of head images were scanned over a 10‐minute interval and 14 whole‐body sets were scanned over a 30‐minute interval. Fourteen sets of MRI images were acquired, and each 3‐modal image set (T1, T2 and FLAIR) was scanned in sequence at time 0, and minutes. The misalignments in these “co‐registered” images were evaluated and corrected using the 3DVIR. Using the head immobilization devices commonly found in diagnostic PET/CT and MRI/MRI imaging, 80%–100% of these “co‐registered” images were identified as misaligned. For PET/CT, the magnitude of misalignment was and for 10‐minute scans, and and for 30‐minute scans. For MRI/MRI, the magnitude was and for 5‐minute scan intervals, and and for 20‐minute intervals. Small, but significant, misalignment is present in the co‐registered diagnostic PET/CT and MRI/MRI images and can be corrected in SRS treatment planning using the volumetric image registration for improved target localization within the clinical error tolerance.PACS numbers: 87.53.Ly, 87.57.nj, 87.57.uk, 87.57.Q‐, 87.61.jc, 87.19.xcConflict of Interest Statement: The authors do not have any conflict of interest on this research report.