Dietary factors and the risk of incident kidney stones in men: New insights after 14 years of follow-up
Dietary factors and the risk of incident kidney stones in men: New insights after 14 years of follow-up
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DOI：
10.1097/01.asn.0000146012.44570.20
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发表时间：
2004-12-01
影响因子：
13.6
通讯作者：
Curhan, GC
中科院分区：
文献类型：
--
作者：
Taylor, EN;Stampfer, MJ;Curhan, GC
肾结石的病因有哪些？由于许多饮食因素的代谢，如钙，可能会随着年龄的变化而变化，饮食和肾结石之间的关系可能在老年人中有所不同。许多饮食因素（如维生素C、镁和动物蛋白）与肾结石形成风险之间的关系也仍然不确定。为了检查饮食因素与男性肾结石发病风险之间的关系，并确定这些关系是否随年龄而变化，对45，619名无肾结石病史的男性进行了前瞻性队列研究。自我管理的食物频率问卷被用来评估每4年的饮食。在477，700人年的随访期间，共记录了1473例有症状的肾结石事件。对于年龄
Diet plays an important role in the pathogenesis of kidney stones. Because the metabolism of many dietary factors, such as calcium, may change with age, the relation between diet and kidney stones may be different in older adults. Uncertainty also remains about the association between many dietary factors, such as vitamin C, magnesium, and animal protein, and the risk of kidney stone formation. To examine the association between dietary factors and the risk of incident, symptomatic kidney stones in men and to determine whether these associations vary with age, a prospective cohort study was conducted of 45,619 men without a history of nephrolithiasis. Self-administered food frequency questionnaires were used to assess diet every 4 yr. A total of 1473 incident symptomatic kidney stones were documented during 477,700 person-years of follow-up. For men aged