Human medial frontal cortex activity predicts learning from errors
Human medial frontal cortex activity predicts learning from errors
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DOI：
10.1093/cercor/bhm219
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发表时间：
2008-08-01
期刊：
影响因子：
3.7
通讯作者：
Mattingley, Jason B.
中科院分区：
文献类型：
--
作者：
Hester, Robert;Barre, Natalie;Mattingley, Jason B.
从错误中学习是人类认知的一个重要特征。它是我们适应不断变化的环境需求和调整行为以实现最佳性能的能力的基础。后内侧额叶皮层（pMFC）已牵连在错误的评估，以控制行为，虽然它以前没有被证明，在这个区域的活动预测学习错误。使用功能性磁共振成像，我们研究了活动的pMFC在联想学习任务中，参与者回忆的空间位置的2位数的目标，并提供了即时反馈的准确性。pMFC内的活动是显着更大的错误，随后纠正比错误，重复。此外，pMFC活动在召回错误预测未来的反应（正确与不正确），尽管一个错误和下一次呈现相同的召回探针之间的相当大的间隔（平均70秒）。海马内的活动也预测了未来的表现，并与错误反馈相关的pMFC活动。在没有不同的错误强化值的情况下，性能预期和pMFC活动之间的关系与错误相关的pMFC活动反映结果“比预期更差”的程度的想法一致。".
Learning from errors is a critical feature of human cognition. It underlies our ability to adapt to changing environmental demands and to tune behavior for optimal performance. The posterior medial frontal cortex (pMFC) has been implicated in the evaluation of errors to control behavior, although it has not previously been shown that activity in this region predicts learning from errors. Using functional magnetic resonance imaging, we examined activity in the pMFC during an associative learning task in which participants had to recall the spatial locations of 2-digit targets and were provided with immediate feedback regarding accuracy. Activity within the pMFC was significantly greater for errors that were subsequently corrected than for errors that were repeated. Moreover, pMFC activity during recall errors predicted future responses (correct vs. incorrect), despite a sizeable interval (on average 70 s) between an error and the next presentation of the same recall probe. Activity within the hippocampus also predicted future performance and correlated with error-feedback-related pMFC activity. A relationship between performance expectations and pMFC activity, in the absence of differing reinforcement value for errors, is consistent with the idea that error-related pMFC activity reflects the extent to which an outcome is "worse than expected.".