Modulation of functional connectivity during the resting state and the motor task
Modulation of functional connectivity during the resting state and the motor task
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DOI：
10.1002/hbm.20012
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发表时间：
2004-05-01
影响因子：
4.8
通讯作者：
Weng, XC
中科院分区：
文献类型：
--
作者：
Jiang, TZ;He, Y;Weng, XC
功能磁共振成像（fMRI）的许多研究表明，即使在静息状态下，运动皮层也构成了一个网络。它从来没有被调查如何网络调制从静息状态到运动任务状态。在这份报告中，通过一种新开发的方法，考虑到n到1的连接，使用1到1的连接措施，而不是传统的成对连接，我们显示了一个大的有组织的功能连接网络的存在与运动功能在静息脑功能磁共振成像。更重要的是，我们发现这种网络可以从有意识的静息状态调节到自主运动状态的规划、启动、协调、指导和终止，表现为不同脑活动中某些脑区的功能连接发生显著变化。此外，这种功能调制的定量描述也已提出。(C)2004 Wiley-Liss，Inc.
Quite a few studies in functional magnetic resonance imaging (fMRI) have tested that, even in a resting state, motor cortices constitute a network. It has never been investigated how the network modulates from the resting state to the motor task state. In this report, by a newly developed approach taking into account n-to-1 connectivity using 1-to-1 connectivity measures instead of conventional pairwise connectivity, we show the existence of a large organized functional connectivity network related to motor function in the resting brain with fMRI. More importantly, we found that such a network can be modulated from a conscious resting state to planning, initiation, coordination, guidance, and termination of voluntary movement state, exhibited by significant changes of functional connectivity of some brain regions in different brain activity. Moreover, a quantitative description of such a functional modulation has also been presented. (C) 2004 Wiley-Liss, Inc.