Enhancing the functional annotation of PDB structures in PDBsum using key figures extracted from the literature
Enhancing the functional annotation of PDB structures in PDBsum using key figures extracted from the literature
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DOI：
10.1093/bioinformatics/btm085
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发表时间：
2007-07-15
期刊：
影响因子：
5.8
通讯作者：
Laskowski, Roman A.
中科院分区：
文献类型：
--
作者：
Laskowski, Roman A.
动机：蛋白质数据库 (PDB) 包含超过 43,800 个通过实验确定的大分子结构及其复合物的 3D 模型。每个 3D 模型都揭示了有关给定分子的功能和生物学意义的一些有趣且重要的内容。通常，此信息的最佳来源是描述它的原始文章，并且通常可以仅从该文章中的一两个图来辨别结构的关键方面。结果：在这里，我们描述了如何在期刊及其出版商的许可下，努力公开这些关键数据，以增强与 PDBsum 数据库中每个 PDB 条目相关的功能信息。
Motivation: The Protein Data Bank (PDB) contains over 43 800 experimentally determined 3D models of macromolecular structures and their complexes. Each 3D model reveals something interesting and important about the given molecule's function and biological significance. Usually the best source of this information is the original article describing it, and it is often possible to discern the key aspects of the structure from just one or two of the figures in that article. Results: Here we describe how, with the permission of the journals and their publishers, we have endeavoured to make these key figures publicly available to enhance the functional information relating to each PDB entry in our PDBsum database.