GenBank
GenBank
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DOI：
10.1093/nar/gku1216
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发表时间：
2015-01-28
影响因子：
14.9
通讯作者：
Sayers, Eric W.
中科院分区：
文献类型：
--
作者：
Benson, Dennis A.;Clark, Karen;Sayers, Eric W.
GenBank（美国国立生物技术信息中心基因序列数据库）（http://www.ncbi.nlm.nih.gov/genbank/）是一个综合性数据库，包含超过30万个已正式描述物种的公开可用的核苷酸序列。这些序列主要通过来自各个实验室的提交以及大规模测序项目（包括全基因组鸟枪法测序和环境采样项目）的批量提交获得。大多数提交是使用基于网络的BankIt或独立的Sequin程序进行的，GenBank工作人员在收到数据时分配登录号。与欧洲核苷酸档案馆和日本DNA数据库的每日数据交换确保了全球覆盖。可通过美国国立生物技术信息中心的Entrez检索系统访问GenBank，该系统整合了来自主要DNA和蛋白质序列数据库的数据以及分类学、基因组、图谱、蛋白质结构和结构域信息，并通过PubMed整合了生物医学期刊文献。BLAST提供对GenBank和其他序列数据库的序列相似性搜索。GenBank数据库的完整双月发布版和每日更新可通过FTP获取。
GenBank (R) (http://www.ncbi.nlm.nih.gov/genbank/) is a comprehensive databases contains publicly available nucleotide sequences for over 300 000 formally described species. These sequences are obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects, including whole-genome shotgun and environmental sampling projects. Most submissions are made using the web-based BankIt or standalone Sequin programs, and GenBank staff assign accession numbers upon data receipt. Daily data exchange with the European Nucleotide Archive and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through the NCBI Entrez retrieval system, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP.