The nature of "spots" on soft lenses.
The nature of "spots" on soft lenses.
复制标题
软镜片上“斑点”的性质。
作者：
D. Doughman;E. Mobilia;D. Drago;V. Havener;M. Gavin
在278例连续治疗性软性透镜配戴者中，19例（6.8%）在透镜的前（空气）表面上出现离散的透镜混浊。如果佩戴超过2周，干眼症患者的发病率上升至16.6%，大泡性角膜病变患者的发病率上升至19%，暴露性角膜炎和倒睫患者的发病率上升至20%。这些混浊与药物无关。扫描电子显微镜显示与这些混浊相关的前透镜表面上的裂纹。透射电子显微镜检查表明，混浊物是无定形材料，接触透镜聚合物延伸到这些混浊物的物质中。脂质，如组织化学方法所示，发现在这些混浊。可能是干燥、透镜表面应力和脂质沉积共同作用改变了塑料的结构并导致这些混浊。
Of 278 consecutive therapeutic soft lens wearers, 19 (6.8%) developed discrete lens opacities on the anterior (air) surface of the lens. The incidence rose to 16.6% in patients fitted for dry eye syndromes, to 19% in bullous keratopathy and to 20% in exposure keratitis and trichiasis, if worn for longer than 2 weeks. These opacities were not associated with medications. Scanning electron microscopy demonstrated cracks on the anterior lens surface associated with these opacities. Transmission electron microscopy demonstrated the opacities to be amorphous material with extensions of the contact lens polymer into the substance of these opacities. Lipid, as demonstrated by histochemical methods, was found in these opacities. It is likely that the combination of dryness, stress on the lens surface, and lipid deposition act to alter the structure of the plastic and cause these opacities.