Impact of dry eye syndrome on vision-related quality of life
Impact of dry eye syndrome on vision-related quality of life
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DOI：
10.1016/j.ajo.2006.11.060
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发表时间：
2007-03-01
影响因子：
4.2
通讯作者：
Schaumberg, Debra A.
中科院分区：
文献类型：
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作者：
Miljanovic, Biljana;Dana, Reza;Schaumberg, Debra A.
目得：评估干眼症（DES）对视力相关生活质量的影响。设计：横断面研究。方法：我们确定了450名妇女健康研究（WHS）和240名医生健康研究（PHS）的参与者并发送了一份补充问卷，询问他们的日常活动受到干眼症症状的限制程度，以及眼睛问题对他们的限制程度在阅读，驾驶，在电脑前工作，他们的专业活动，和看电视。根据设计，三分之一的研究受试者有临床诊断的DES或严重症状，三分之二没有。我们使用逻辑回归研究DES与报告的问题，在每个队列的日常活动和汇总估计使用荟萃分析methods.Results的关系：邀请的参与者，85%完成了补充问卷，包括135 WHS和55 PHS参与者DES，和250 WHS和149 PHS参与者没有DES。控制年龄、糖尿病、高血压和其他因素后，DES患者更可能报告阅读问题（[比值比] OR = 3.64，95% [置信区间] CI 2.45至5.40，P
PURPOSE: To evaluate the impact of dry eye syndrome (DES) on vision-associated quality of life.DESIGN: Cross-sectional study.METHODS: We identified 450 participants in the Women's Health Study (WHS) and 240 participants in the Physicians' Health Study (PHS) and sent a supplementary questionnaire asking how much their everyday activities were limited by symptoms of dry eye and to what degree problems with their eyes limited them in reading, driving, working at the computer, their professional activity, and watching television. By design, one-third of study subjects had clinically diagnosed DES or severe symptoms and two,thirds did not. We used logistic regression to examine relationships of DES with reported problems with everyday activities in each cohort and pooled estimates using meta-analysis methods.RESULTS: Of the participants invited, 85% completed the supplementary questionnaire, including 135 WHS and 55 PHS participants with DES, and 250 WHS and 149 PHS participants without DES. Controlling for age, diabetes, hypertension, and other factors, those with DES were more likely to report problems with reading ([odds ratio] OR = 3.64, 95% [confidence interval] CI 2.45 to 5.40, P