Development of Rapid Determination of 18 Phthalate Esters in Edible Vegetable Oils by Gas Chromatography Tandem Mass Spectrometry
Development of Rapid Determination of 18 Phthalate Esters in Edible Vegetable Oils by Gas Chromatography Tandem Mass Spectrometry
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DOI：
10.1021/jf3053884
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发表时间：
2013-02-13
影响因子：
6.1
通讯作者：
Wang, Li
中科院分区：
文献类型：
--
作者：
Liu, Yinping;Wang, Shuhui;Wang, Li
建立了食用植物油中18种邻苯二甲酸酯（PAEs）的同时快速测定方法。油样经溶剂萃取后，再经固相萃取进一步净化。浓缩后，提取物直接进样到气相色谱串联质谱（GC-MS/MS）中，采用正离子电子轰击（EI）模式。方法定量限为0.01 ~ 0.1 mg/kg。定量回收率范围为63.9%至115.3%，通过分析加标油。相对标准偏差小于15%（n = 6）。该方法有可能克服大量脂质和色素的干扰。应用于真实的样品中，结果表明该方法可用于邻苯二甲酸酯类化合物的测定和确证。
A simultaneous and fast determination of 18 phthalic acid esters (PAEs) in edible vegetable oils was developed. After solvent extraction, the PAEs in the oil sample were further cleaned up by solid-phase extraction. After concentration, the extract was directly injected into gas chromatography tandem mass spectrometry (GC-MS/MS) in positive-ion electron impact (El) mode. Method quantification limits of 18 PAEs were between 0.01 and 0.1 mg/kg. Quantitative recoveries ranging from 63.9 to 115.3% were obtained by analysis of spiked oil. The relative standard deviations were less than 15% (n = 6). The method could potentially overcome the interference from large amounts of lipids and pigment. It was applied to real sample and shown to be a rapid and reliable alternative for determination and confirmation of PAEs in routine analysis.