Comorbidity with low back pain - A cross-sectional population-based survey of 12-to 22-year-olds
Comorbidity with low back pain - A cross-sectional population-based survey of 12-to 22-year-olds
复制标题
DOI：
10.1097/01.brs.0000129230.52977.86
复制
发表时间：
2004-07-01
期刊：
影响因子：
3
通讯作者：
Manniche, C
中科院分区：
文献类型：
--
作者：
Hestbaek, L;Leboeuf-Yde, C;Manniche, C
研究设计。横断面，以人口为基础的调查。探讨青少年腰痛的合并症模式。背景资料摘要。腰痛通常作为一个特定的和独立的实体来处理。然而，现有文献显示，腰痛的合并症很常见，这表明腰痛可能是一般健康的更广泛模式的一部分。目前的知识是基于对成年人口的研究；因此，这种关联可以用工作和生活方式因素来解释。在这一领域，关于受这些因素影响的受试者的信息还很缺乏。在丹麦人口双胞胎登记处登记的双胞胎中进行了一项关于一般健康状况的问卷调查，包括腰痛。通过逻辑回归和有限混合模型计算疾病之间的关联，并调查合并症的模式。最后进行了一项双对照研究。共有9567名年龄在12岁到22岁之间的人回答了调查问卷。腰痛与哮喘和头痛/偏头痛之间存在正相关，这主要是因为研究参与者患有几种疾病。腰痛和特应性皮炎/花粉热之间没有关联。另外两种疾病的存在比只有一种其他疾病的存在增加了腰痛的可能性。有限混合模型表明，属于虚弱亚组的概率从13岁时的60%下降到21岁时的25%，在虚弱亚组中，几乎所有人都报告了老年时的腰痛和头痛。此外，腰痛持续时间的增加增加了患其他疾病的可能性。双对照研究的结果相似。年轻人更容易患哮喘和头痛，但如果他们有腰痛，就不会患特应性皮炎/花粉热。所有被调查的疾病都集中在一些个体身上。应该考虑这些看似独立的疾病的共同起源模型。
Study Design. Cross-sectional, population-based survey.Objectives. To investigate the pattern of comorbidity with low back pain in adolescents.Summary of Background Data. Low back pain is usually dealt with as a specific and independent entity. However, the existing literature shows comorbidity to be common with low back pain, suggesting that low back pain may be part of a broader pattern of general health. The present knowledge is based on studies of adult populations; therefore, associations could be explained by work and lifestyle factors. Information in this area is lacking regarding subjects still unaffected by such factors.Methods. A questionnaire-survey about general health, including low back pain, was carried out among twins registered in the population-based Danish Twin Registry. Associations between disorders were calculated and patterns of comorbidity investigated, by means of logistic regression and a finite mixture model. Finally a twin-control study was conducted.Results. A total of 9,567 individuals, 12 to 22 years of age, responded to the questionnaire. Positive associations between low back pain and asthma and headache/ migraine were demonstrated, mainly because of study participants with several disorders. No association between low back pain and atopic dermatitis/hay fever was found. The presence of two other disorders increased the probability of low back pain considerably more than the presence of only one other disorder. The finite mixture model indicated that the probability of belonging to a frail subgroup decreased from 60% at age 13 to 25% at age 21, and in the frail subgroups nearly all report low back pain and headache in the older ages. Furthermore, increasing duration of low back pain increased the likelihood of having other disorders. Results from the twin-control study were similar.Conclusion. Young people are more likely to suffer from asthma and headache, but not from atopic dermatitis/ hay fever, if they have low back pain. All of the investigated disorders cluster in some individuals. A model of common origin for these seemingly independent disorders should be considered.