2D DNA lattices constructed from two-tile DAE-O systems possessing circular central strands
2D DNA lattices constructed from two-tile DAE-O systems possessing circular central strands
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由具有圆形中心链的双瓦 DAE-O 系统构建的 2D DNA 晶格
DOI：
10.1039/c6nr06745j
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发表时间：
2016-01-01
期刊：
影响因子：
6.7
通讯作者：
Xiao, Shou-Jun
中科院分区：
文献类型：
--
作者：
Wang, Meng;Huang, Haofu;Xiao, Shou-Jun
我们报道了一个经典的双瓦系统DAE- o（双交叉，反平行，偶数半转瓷砖与奇数半转连接）构建规则的单晶2D（二维）DNA晶格，分别使用42-，64-和84-nt（核苷酸）的预环寡核苷酸作为DAE瓦中的中心环链。以42-和64-nt为中心链的DAE瓷砖，无论是圆形还是线性，都能很好地生长规则的单晶晶格。然而，包括圆形84-nt作为中心链的DAE瓦片生长单晶晶格，包括线性84-nt作为中心链的DAE瓦片生长多晶二维晶格。DAE瓷砖的横向刚度的细微差异与双轴有关，被认为是形态差异的原因。
We reported a classical two-tile system of DAE-O (doublecross-over, antiparallel, and even half-turns tiles with odd half-turns connection) to construct regular single crystalline 2D (two dimensional) DNA lattices, using pre-circularised oligonucleotides of 42-, 64-, and 84-nt (nucleotides) as the central looped strands in DAE tiles respectively. DAE tiles with 42- and 64-nt as central strands, either in circular form or in linear form, grew regular single crystalline lattices well. However DAE tiles including a circular 84-nt as the central strand grew single crystalline lattices, those including a linear 84-nt as the central strand grew polycrystalline 2D lattices. A subtle difference in the lateral rigidity of DAE tiles with regard to the duplex axis was suggested to be the cause of the morphological difference.