Is routine frozen section analysis necessary in patients with non-endometrioid cancer or grade 3 endometrioid cancer?
Is routine frozen section analysis necessary in patients with non-endometrioid cancer or grade 3 endometrioid cancer?
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非子宫内膜样癌或 3 级子宫内膜样癌患者是否需要进行常规冰冻切片分析？
DOI：
10.1002/ijgo.13712
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发表时间：
2022-03
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影响因子：
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探讨子宫内膜癌患者冰冻切片（FS）结果与最终病理结果之间与类型和亚型相关的准确性，并建议是否应常规进行。回顾性数据收集了 184 名在单一中心接受手术的子宫内膜癌患者（2014 年 1 月至 2018 年 12 月）。将 FS 结果与最终病理结果在组织型、肿瘤分级和浸润深度方面进行比较，以确定 FS 分析的准确性。对 141 名 (76.6%) 患者进行冰冻切片分析。 FS与最终病理结果在组织类型、肿瘤分级和浸润深度方面的准确率和κ值分别为87.23%、81.15%和98.2%以及0.41、0.7和0.9（P < 0.001）。 18 例术前患有非子宫内膜样癌（non-EC）的患者中，6 例接受了 FS 分析，最终病理证实 3 例为 EC，其中 75% 通过 FS 分析检测到。 19例术前3级EC的患者中有8例进行了FS分析，准确率为87.5%。术中 FS 分析是一种可靠的方法，可以帮助术中决策。对于非 EC 和 3 级 EC 患者应常规进行。
To explore the accuracy related to type and subtype between frozen section (FS) results and final pathology results in patients with endometrial cancer and to suggest whether it should be routinely performed. Retrospective data were collected from 184 patients with endometrial cancer who underwent surgery at a single center (January 2014–December 2018). FS results were compared with the final pathology results with respect to histotype, tumor grade, and depth of invasion to define the accuracy of FS analysis. Frozen section analysis was performed in 141 (76.6%) patients. The accuracy rates and κ values between the FS and final pathology results with respect to histotype, tumor grade, and depth of invasion were 87.23%, 81.15%, and 98.2% and 0.41, 0.7, and 0.9, respectively (P < 0.001). Among the 18 patients with preoperative non‐endometrioid cancer (non‐EC), six underwent FS analysis, and final pathology confirmed EC in three, of whom 75% were detected by FS analysis. Eight of 19 patients with preoperative grade 3 EC underwent FS analysis and the accuracy rate was 87.5%. Intraoperative FS analysis is a reliable method that can help intraoperative decision making. It should be performed routinely in patients with non‐EC and grade 3 EC.
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影响因子：
3.5
作者：
Desouki, Mohamed Mokhtar;Li, Zaibo;Fadare, Oluwole
通讯作者：
Fadare, Oluwole
影响因子：
4.7
作者：
Poelcher, M.;Rottmann, M.;Engel, J.
通讯作者：
Engel, J.
影响因子：
3.5
作者：
Khalifa, Mahmoud A.;Salama, Sherine;Winterhoff, Boris
通讯作者：
Winterhoff, Boris
DOI：
10.1111/j.1471-0528.2001.00196.x
发表时间：
2001-08-01
期刊：
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
影响因子：
--
作者：
Quinlivan, JA;Petersen, RW;Nicklin, JL
通讯作者：
Nicklin, JL
影响因子：
7.2
作者：
Case, Ashley S.;Rocconi, Rodney P.;Huh, Warner K.
通讯作者：
Huh, Warner K.