Neuromuscular incoordination in musician's dystonia
Neuromuscular incoordination in musician's dystonia
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DOI：
10.1016/j.parkreldis.2019.05.011
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发表时间：
2019-08-01
影响因子：
4.1
通讯作者：
Furuya，Shinichi
中科院分区：
文献类型：
--
作者：
Oku，Takanori;Furuya，Shinichi
IntroductionThe本研究的目的是定义特定于局部任务特异性肌张力障碍（FTSD）的肌肉活动模式，并根据其与精细运动控制或补偿的退化的关联对其进行分类。MethodsWhile 13名FTSD钢琴家和10名专家钢琴家在钢琴上演奏了几首旋律，记录了8个内在和外在手指肌肉的活动和击键动作。为了排除专业知识的混淆影响，12名业余钢琴家也参加了比赛。的肌肉活动进行了分析，与非负矩阵分解，一个无监督的分类技术，和多元回归analysis.Results6种不同的模式的肌肉协调被确定，每一个负责与每一个五个数字和共同收缩之间的拮抗对手指的肌肉。健康的钢琴家和钢琴家与FTSD之间的比较没有发现FTSD相关的共同收缩的证据。肌肉协调和击键运动之间的回归分析进一步确定了23.4%和20.8%的FTSD相关的肌肉活动变化与运动退化（即手指运动从屈曲到伸展的延迟过渡）和补偿有关。前者不仅与过度激活的屈肌，但也与减少激活的伸肌。ConclusionsThe本研究指定神经肌肉适应不良相关的FTSD症状，这表明，肌肉不协调，而不是肌肉共同收缩特征的病理特征FTSD在音乐家。
IntroductionThe present study aims to define patterns of muscular activities specific to focal task-specific dystonia (FTSD), and classify them according to their association with the degradation of fine motor control or compensation for it.MethodsWhile thirteen pianists with FTSD and ten expert pianists played several melodies on the piano, the activity of eight intrinsic and extrinsic finger muscles and the key-striking movements were recorded. To exclude the confounding effects of expertise, twelve amateur pianists also participated. The muscular activities were analyzed with a non-negative matrix factorization, an unsupervised classification technique, and multiple regression analysis.ResultsSix different patterns of muscular coordination were identified, each of which was responsible for the keystroke with each of the five digits and co-contraction between an antagonistic pair of finger muscles. A comparison between the healthy pianists and pianists with FTSD found no evidence of FTSD-related elevation of the co-contraction. A regression analysis between the muscular coordination and the key-striking movements further identified 23.4% and 20.8% of the FTSD-related changes in the muscular activity as associated with the movement degradation (i.e. delayed transition of the finger motion from flexion to extension) and compensation for it, respectively. The former was associated not only with hyper-activation of the flexor, but also with reduced-activation of the extensor.ConclusionsThe present study specified neuromuscular maladaptation relevant to the FTSD symptom, which suggests that muscular incoordination rather than muscular co-contraction characterizes pathological feature of FTSD in musicians.