Review of Dielectrophoretic Manipulation of Micro and Nanomaterials: Fundamentals, Recent Developments, and Challenges
Review of Dielectrophoretic Manipulation of Micro and Nanomaterials: Fundamentals, Recent Developments, and Challenges
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DOI：
10.1109/tbme.2022.3183167
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发表时间：
2023-01-01
影响因子：
4.6
通讯作者：
Hihath, Joshua
中科院分区：
文献类型：
--
作者：
Ghomian, Taher;Hihath, Joshua
本文综述了介电电泳在微纳米材料操作中的应用。介电电泳是一种使用非均匀电场进行材料操作的公知技术。该场可以向电介质材料施加力，并将它们移向预定义的位置。通过电极或绝缘体的特定布置以及材料的介电性质来控制电场的图案及其强度，沿着允许各种操纵功能，包括捕获、分离和运输。微加工技术的发展极大地提高了介电电泳领域的研究质量，以精确操纵微和纳米材料。后来，微流体装置的出现为可靠和实用的装置提供了一个极好的平台。修改电极的形状、几何形状和材料，将电极与样品隔离，在电场内并入绝缘体的特定布置，以及原位监测操作是用于克服介电泳装置中的常见问题或与特定样品和操纵功能相关联的问题的一些方法。该领域研究的目标是设计实用，高通量和廉价的设备，可靠地操纵微米和纳米材料。因此，本文综述了介电电泳领域的最新发现和进展。特别是，工作原理，技术实现细节，目前的状态，以及基于电极和基于绝缘体的介电泳器件的操作和制造方面的问题和挑战进行了讨论。
This paper reviews the state-of-the-art methods of dielectrophoresis for micro- and nanomaterial manipulation. Dielectrophoresis is a well-known technique for material manipulation using a nonuniform electric field. This field can apply a force to dielectric materials and move them toward a predefined location. Controlling the pattern of the electric field and its intensity, achieved by a specific arrangement of electrodes or insulators, along with the dielectric properties of the materials allows a variety of manipulation functions including trapping, separation, and transportation. The development of microfabrication techniques has significantly improved the research quality in the field of dielectrophoresis for precisely manipulating micro and nanomaterials. Later, the advent of microfluidic devices provided an excellent platform for reliable and practical devices. Modifying the shape, geometry, and material of the electrodes, isolating the electrodes from the sample, incorporating a particular arrangement of insulators within the electric field, and monitoring the operation in situ are some of the methods utilized for overcoming common problems in dielectrophoretic devices or the problems associated with a specific sample and the manipulation function. The goal of the research in this field is to design practical, high throughput, and inexpensive devices that reliably manipulate micro and nanomaterials. Accordingly, this review aims to represent latest findings and advancements in the field of dielectrophoresis. In particular, the working principles, technical implementation details, current status, and the issues and challenges of dielectrophoretic devices for electrode-based and insulator-based dielectrophoresis in terms of operation and fabrication are discussed.