High-flow nasal cannula oxygen therapy for acute exacerbation of interstitial pneumonia: A case series
High-flow nasal cannula oxygen therapy for acute exacerbation of interstitial pneumonia: A case series
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DOI：
10.1016/j.resinv.2015.09.005
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发表时间：
2016-03-01
影响因子：
3.1
通讯作者：
Asano, Koichiro
中科院分区：
文献类型：
--
作者：
Horio, Yukihiro;Takihara, Takahisa;Asano, Koichiro
我们报告了3例（均为男性，年龄：69-81岁）间质性肺炎（AEIP）急性加重的病例，采用高流量鼻插管（HFNC）成功治疗，该鼻插管可输送加热的加湿气体，吸入氧气分数（FIO 2）高达1.0（100%）。在非再呼吸面罩下氧合不足;然而，引入FIO 2为0.7-1.0（流速：40 L/min）的HFNC改善了氧合，并且耐受性良好，直到血液中的氧分压/FIO 2比值增加（21 - 26天）。因此，HFNC可能是AEIP管理的有效且耐受性良好的治疗方法。(C)2015日本呼吸学会Elsevier B. V.出版，保留所有权利。
We report 3 cases (all men, age: 69-81 years) of acute exacerbation of interstitial pneumonia (AEIP) that were successfully treated with a high-flow nasal cannula (HFNC), which delivers heated, humidified gas at a fraction of inspired oxygen (FIO2) up to 1.0 (100%). Oxygenation was insufficient under non-rebreathing face masks; however, the introduction of HFNC with an FIO2 of 0.7-1.0 (flow rate: 40 L/min) improved oxygenation and was well-tolerated until the partial pressure of oxygen in blood/FIO2 ratio increased (between 21 and 26 days). Thus, HFNC might be an effective and well-tolerated therapeutic addition to the management of AEIP. (C) 2015 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.