Further characterizations of bleomycin-sensitive (blm) mutants of Saccharomyces cerevisiae with implications for a radiomimetic model.
Further characterizations of bleomycin-sensitive (blm) mutants of Saccharomyces cerevisiae with implications for a radiomimetic model.
复制标题
酿酒酵母博莱霉素敏感 (blm) 突变体的进一步表征及其对放射模拟模型的影响。
DOI：
10.1128/jb.173.11.3605-3608.1991
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发表时间：
1991
影响因子：
3.2
通讯作者：
Moore,CW
中科院分区：
文献类型：
--
作者：
Moore,CW
直接选择的12个突变（blm）赋予超敏反应的博莱霉素在酿酒酵母的致死作用导致突变体表现出交叉超敏反应的电离辐射和过氧化氢。剩余的突变没有赋予交叉超敏反应辐射。所有blm突变是隐性的，除了共显性blm 3 -1，并分配到7个互补组。
Direct selection for 12 mutations (blm) conferring hypersensitivities to lethal effects of bleomycins in Saccharomyces cerevisiae resulted in mutants exhibiting cross-hypersensitivity to ionizing radiation and hydrogen peroxide. Remaining mutations did not confer cross-hypersensitivity to radiation. All blm mutations were recessive, except codominant blm3-1, and were assigned to seven complementation groups.