RADIOFREQUENCY PLASMA DEPOSITION OF OXYGEN-CONTAINING FILMS ON POLYSTYRENE AND POLY(ETHYLENE-TEREPHTHALATE) SUBSTRATES IMPROVES ENDOTHELIAL-CELL GROWTH
RADIOFREQUENCY PLASMA DEPOSITION OF OXYGEN-CONTAINING FILMS ON POLYSTYRENE AND POLY(ETHYLENE-TEREPHTHALATE) SUBSTRATES IMPROVES ENDOTHELIAL-CELL GROWTH
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DOI：
10.1002/jbm.820241207
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发表时间：
1990-12-01
期刊：
影响因子：
--
通讯作者：
HORBETT, TA
中科院分区：
文献类型：
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作者：
ERTEL, SI;RATNER, BD;HORBETT, TA
聚苯乙烯和聚（对苯二甲酸乙二醇酯）基板进行了修改，通过射频等离子体沉积与有机蒸汽组成的碳，氧，氢（丙酮，甲醇，戊二醛，甲酸，烯丙醇，环氧乙烷）。处理导致至少100埃的膜沉积。表面含有高达26%的原子氧。观察到高的氧掺入的蒸汽具有大的氧碳比。在丙酮、甲醇和戊二醛薄膜上测量的牛主动脉内皮细胞生长与处理表面的氧含量呈线性相关。通过将氮气混合到用于等离子体沉积的有机蒸气中，将氮气结合到表面中。所得含氮底物对血清纤连蛋白表现出高亲和力，但细胞生长适中。
Polystyrene and poly(ethylene terephthalate) substrates were modified by radiofrequency plasma deposition with organic vapors comprised of carbon, oxygen, and hydrogen (acetone, methanol, glutaraldehyde, formic acid, allyl alcohol, and ethylene oxide). The treatments resulted in the deposition of a film at least 100 .ANG. thick containing up to 26% atomic oxygen at the surface. A high oxygen incorporation was observed for vapors with a large oxygen-to-carbon ratio. Bovine aortic endothelial cell growth measured on acetone, methanol, and glutaraldehyde films was linearly correlated with the oxygen content of the treated surfaces. Nitrogen was incorporated in the surface by blending nitrogen gas into the organic vapor used for plasma deposition. The resulting nitrogen-containing substrates exhibited a high affinity for serum fibronectin but a moderate cell growth.