PSYCHOSOCIAL INFLUENCES ON MORTALITY AFTER MYOCARDIAL-INFARCTION

PSYCHOSOCIAL INFLUENCES ON MORTALITY AFTER MYOCARDIAL-INFARCTION
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DOI:
10.1056/nejm198408303110902
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发表时间:
1984-01-01
影响因子:
158.5
通讯作者:
CHAUDHARY, BS
CHAUDHARY, BS
中科院分区:
医学1区
文献类型:
--
作者:
RUBERMAN, W;WEINBLATT, E;CHAUDHARY, BS

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对2320名急性心肌梗死男性幸存者的心理社会采访,他们是β-Blocker心脏病发作试验的参与者,允许定义与增加3年死亡率风险密切相关的2个变量。在控制了其他重要预后因素的情况下,被归类为社交孤立和高度生活压力的患者的死亡风险是压力和隔离程度较低的男性的4倍以上。在这一人群中,教育与死亡率呈负相关,反映了明确的心理社会特征的流行程度的梯度。高水平的压力和社会孤立在受教育程度最低的男性中最为普遍,在受教育程度最高的男性中最不普遍。与压力和社会隔离相关的风险增加既适用于总死亡,也适用于心脏猝死,并在因急性脑梗塞住院期间脑室异位程度高和低的男性中得到注意。
Psychosocial interviews with 2320 male survivors of acute myocardial infarction, participants in the .beta.-Blocker Heart Attack Trial, permitted the definition of 2 variables strongly associated with an increased 3-yr mortality risk. With other important prognostic factors controlled for, the patients classified as being socially isolated and having a high degree of life stress had more than 4 times the risk of death of the men with low levels of both stress and isolation. An inverse association of education with mortality in this population reflected the gradient in the prevalence of the defined psychosocial characteristics. High levels of stress and social isolation were most prevalent among the least-educated men and least prevalent among the best-educated. The increase in risk associated with stress and social isolation applied both to total deaths and to sudden cardiac deaths and was noted among men with both high and low levels of ventricular ectopy during hospitalization for the acute infarction.