Joint Angle Variability Is Altered in Patients with Peripheral Artery Disease after Six Months of Exercise Intervention.
Joint Angle Variability Is Altered in Patients with Peripheral Artery Disease after Six Months of Exercise Intervention.
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DOI：
10.3390/e24101422
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发表时间：
2022-10-06
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--
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监督运动疗法(SET)是改善周围动脉疾病(PAD)患者步行能力的一种保守的非手术治疗策略。PAD患者的步态可变性发生改变，但SET对步态可变性的影响尚不清楚。43名患有PAD的跛行患者在为期6个月的SET程序开始前和结束后立即进行了步态分析。用样本熵和踝关节、膝关节和髋关节角度时间序列的最大Lyapunov指数来评估步态的非线性变异性。还计算了这三个关节角度的运动范围时间序列的线性平均值和变异性。双因素方差重复测量分析确定了干预和关节位置对线性和非线性因变量的影响。SET后，步行规律性降低，而稳定性未受影响。与膝关节和髋关节相比，踝关节的非线性变异性有增加的趋势。线形测量在SET后没有改变，除了膝关节角度，在干预后变化的幅度增加。一项为期六个月的SET计划产生了朝着健康对照组方向的步态可变性的变化，这表明总的来说，SET改善了患有PAD的个人的步行能力。
Supervised exercise therapy (SET) is a conservative non-operative treatment strategy for improving walking performance in patients with peripheral artery disease (PAD). Gait variability is altered in patients with PAD, but the effect of SET on gait variability is unknown. Forty-three claudicating patients with PAD underwent gait analysis before and immediately after a 6-month SET program. Nonlinear gait variability was assessed using sample entropy, and the largest Lyapunov exponent of the ankle, knee, and hip joint angle time series. Linear mean and variability of the range of motion time series for these three joint angles were also calculated. Two-factor repeated measure analysis of variance determined the effect of the intervention and joint location on linear and nonlinear dependent variables. After SET, walking regularity decreased, while the stability remained unaffected. Ankle nonlinear variability had increased values compared with the knee and hip joints. Linear measures did not change following SET, except for knee angle, in which the magnitude of variations increased after the intervention. A six-month SET program produced changes in gait variability toward the direction of healthy controls, which indicates that in general, SET improved walking performance in individuals with PAD.
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