Do electronic cigarettes increase cigarette smoking in UK adolescents? Evidence from a 12-month prospective study.
Do electronic cigarettes increase cigarette smoking in UK adolescents? Evidence from a 12-month prospective study.
复制标题
DOI：
10.1136/tobaccocontrol-2016-053539
复制
发表时间：
2017-08-17
期刊：
影响因子：
5.2
通讯作者：
Siddiqi K
中科院分区：
文献类型：
--
作者：
Conner M;Grogan S;Simms-Ellis R;Flett K;Sykes-Muskett B;Cowap L;Lawton R;Armitage CJ;Meads D;Torgerson C;West R;Siddiqi K
在横断面调查中，越来越多的青少年报告同时使用电子烟和香烟。这项研究评估了青少年电子烟的使用是否与吸烟的开始或升级有关。数据来自英格兰20所学校的2836名青少年（基线年龄为13-14岁）。在基线时，评估了呼吸一氧化碳水平，自我报告的电子烟和香烟使用，性别，年龄，朋友和家人吸烟，对香烟使用的信念和接受免费学校餐的百分比（社会经济地位的衡量标准）。在12个月的随访中，通过呼吸一氧化碳水平评估并验证了自我报告的吸烟情况。基线时，34.2%的青少年报告曾使用电子烟（16.0%仅使用电子烟）。基线曾经使用电子烟与随后的开始密切相关（n=1726; OR 5.38，95% CI 4.02 - 7.22;控制协变量，OR 4.06，95% CI 2.94 - 5.60）和递增（n=318; OR 1.91，95% CI 1.14至3.21;控制协变量后，该效应变得不显著，OR 1.39，95% CI 0.97至1.82）。这是第一项报告英国青少年曾经使用电子烟与开始和升级吸烟之间的前瞻性关系的研究。曾经使用过电子烟与开始吸烟密切相关，但与吸烟升级的关系更为温和。需要在更广泛的青少年年龄范围内进行更长时间的后续研究。
In cross-sectional surveys, increasing numbers of adolescents report using both electronic cigarettes (e-cigarettes) and cigarettes. This study assessed whether adolescent e-cigarette use was associated prospectively with initiation or escalation of cigarette use. Data were from 2836 adolescents (aged 13–14 years at baseline) in 20 schools in England. At baseline, breath carbon monoxide levels, self-reported e-cigarette and cigarette use, sex, age, friends and family smoking, beliefs about cigarette use and percentage receiving free school meals (measure of socioeconomic status) were assessed. At 12-month follow-up, self-reported cigarette use was assessed and validated by breath carbon monoxide levels. At baseline, 34.2% of adolescents reported ever using e-cigarettes (16.0% used only e-cigarettes). Baseline ever use of e-cigarettes was strongly associated with subsequent initiation (n=1726; OR 5.38, 95% CI 4.02 to 7.22; controlling for covariates, OR 4.06, 95% CI 2.94 to 5.60) and escalation (n=318; OR 1.91, 95% CI 1.14 to 3.21; controlling for covariates, this effect became non-significant, OR 1.39, 95% CI 0.97 to 1.82) of cigarette use. This is the first study to report prospective relationships between ever use of e-cigarettes and initiation and escalation of cigarette use among UK adolescents. Ever use of e-cigarettes was robustly associated with initiation but more modestly related to escalation of cigarette use. Further research with longer follow-up in a broader age range of adolescents is required.