Responses of neurons in macaque area V4 during memory-guided visual search
Responses of neurons in macaque area V4 during memory-guided visual search
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DOI：
10.1093/cercor/11.8.761
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发表时间：
2001-08-01
期刊：
影响因子：
3.7
通讯作者：
Desimone, R
中科院分区：
文献类型：
--
作者：
Chelazzi, L;Miller, EK;Desimone, R
在具有许多不同对象的典型场景中，需要注意机制来选择相关对象进行视觉处理和行为控制。为了测试V4区在基于非空间特征的对象选择中的作用，我们使用视觉搜索范式记录了猴子的V4神经元。线索刺激呈现在注视的中心，随后是一个空白的延迟期。在延迟之后，一个双刺激阵列被呈现在中心凹外，猴子因为检测到与线索匹配的目标刺激而得到奖励。该阵列由一个"好"刺激（当单独呈现时有效驱动细胞）和一个"差"刺激（当单独呈现时无效驱动细胞）组成。当选择阵列呈现在神经元的感受野（RF）中时，许多叫声显示出刺激之间的抑制性相互作用以及强烈的注意力效应。在阵列开始的150 - 200 ms内，通过目标刺激确定对阵列的响应。如果目标是好的刺激，对阵列的反应就等于对单独呈现的好刺激的反应。如果目标是不良刺激，则反应接近于对单独呈现的刺激的反应。因此，非目标刺激的影响被过滤掉。当不良刺激位于RF之外时，这些效应会减少或消除，因此不再竞争细胞的反应。总的来说，结果支持一个“有偏见的竞争”模型的注意力，根据该模型，在视觉领域中的对象在皮层中的代表竞争，这种竞争是偏向于有利于行为相关的对象。
In a typical scene with many different objects, attentional mechanisms are needed to select relevant objects for visual processing and control over behavior. To test the role of area V4 in the selection of objects based on non-spatial features, we recorded from V4 neurons in the monkey, using a visual search paradigm. A cue stimulus was presented at the center of gaze, followed by a blank delay period. After the delay, a two-stimulus array was presented extrafoveally, and the monkey was rewarded for detecting the target stimulus matching the cue. The array was composed of one 'good' stimulus (effective in driving the cell when presented alone) and one 'poor' stimulus (ineffective in driving the cell when presented alone). When the choice array was presented in the receptive field (RF) of the neuron, many calls showed suppressive interactions between the stimuli as well as strong attention effects. Within 150-200 ms of array onset, responses to the array were determined by the target stimulus. If the target was the good stimulus, the response to the array became equal to the response to the good stimulus presented alone. If the target was the poor stimulus, the response approached the response to that stimulus presented alone. Thus the influence of the nontarget stimulus was filtered out. These effects were reduced or eliminated when the poor stimulus was located outside the RF and, therefore, no longer competing for the cell's response. Overall, the results support a 'biased competition' model of attention, according to which objects in the visual field compete for representation in the cortex, and this competition is biased in favor of the behaviorally relevant object.