Novel technique for cardiac electromechanical mapping with magnetic resonance imaging tagging and an epicardial electrode sock
Novel technique for cardiac electromechanical mapping with magnetic resonance imaging tagging and an epicardial electrode sock
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DOI：
10.1114/1.1560618
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发表时间：
2003-04-01
影响因子：
3.8
通讯作者：
McVeigh, ER
中科院分区：
文献类型：
--
作者：
Faris, OP;Evans, FJ;McVeigh, ER
现在，使用磁共振成像标记和多电极心外膜袜子，可以几乎同时测量整个心室表面的电和机械激活。这项新的机电标测技术在心室起搏的犬心脏上得到了演示。将128个电极的心外膜套和起搏电极放置在4只麻醉犬的心脏上。在磁共振扫描仪中，在右室起搏下采集标记电影图像(8~15ms/帧)和袜子电极记录(1000 Hz)，并在时间上参考起搏刺激。电子记录是在图像采集的间歇性中断期间获得的，因此两个数据集代表相同的生理状态。由于电极在图像中不可见，电极记录和电影图像与附着在袜子上的Gd-DTPA标记进行空间配准。在对应于电极的位置计算周向应变。对于每个电极位置，计算了电和机械激活时间，并证明了两种激活模式之间的关系。这种方法有望改善对心脏电激活和收缩模式之间关系的理解。(C)2003年生物医学工程学会。
Near-simultaneous measurements of electrical and mechanical activation over the entire ventricular surface are now possible using magnetic resonance imaging tagging and a multielectrode epicardial sock. This new electromechanical mapping technique is demonstrated in the ventricularly paced canine heart. A 128-electrode epicardial sock and pacing electrodes were placed on the hearts of four anesthetized dogs. In the magnetic resonance scanner, tagged cine images (8-15 ms/frame) and sock electrode recordings (1000 Hz) were acquired under right-ventricular pacing and temporally referenced to the pacing stimulus. Electrical recordings were obtained during intermittent breaks in image acquisition, so that both data sets represented the same physiologic state. Since the electrodes were not visible in the images, electrode recordings and cine images were spatially registered with Gd-DTPA markers attached to the sock. Circumferential strain was calculated at locations corresponding to electrodes. For each electrode location, electrical and mechanical activation times were calculated and relationships between the two activation patterns were demonstrated. This method holds promise for improving understanding of the relationships between the patterns of electrical activation and contraction in the heart. (C) 2003 Biomedical Engineering Society.