The correlation between the high-intensity zone on a T2-weighted MRI and positive outcomes of discography: a meta-analysis
The correlation between the high-intensity zone on a T2-weighted MRI and positive outcomes of discography: a meta-analysis
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DOI：
10.1186/s13018-017-0523-1
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发表时间：
2017-02-08
影响因子：
2.6
通讯作者：
Li, Hongjie
中科院分区：
文献类型：
--
作者：
Fang, Chunyang;Zhang, Wenbin;Li, Hongjie
背景资料：本荟萃分析旨在评估腰椎MRI高强度区（HIZ）与discografic.Methods之间的相关性：我们使用以下检索词对PubMed、MEDLINE、Embase和ScienceDirect数据库进行了电子检索，检索时间分别为2016年10月至2016年10月：“腰痛”、“椎间盘源性腰痛”、“HIZ或高强度区”和“椎间盘造影”。人工检索相关期刊和会议记录。两名评价者独立评估研究的质量，从纳入的研究中提取数据，并分析数据。荟萃分析结果表明，HIZ与椎间盘形态异常之间存在显著相关性和统计学显著相关性（OR = 47.79，95%CI：17.07 ~ 133.77，P < 0.00001），HIZ与疼痛再现（OR = 8.65，95%CI：6.01 ~ 15.23，P < 0.00001），HIZ和异常形态疼痛再现（OR = 11.74，95%CI：1.99 ~ 69.36，P = 0.007）。结论：腰椎MRI T2加权像上HIZ的存在提示椎间盘形态异常。HIZ和疼痛再现之间存在很强的关系。HIZ可作为预测椎间盘源性腰痛的有效指标。
Background: This meta-analysis aimed to assess the correlation between the high-intensity zone (HIZ) of a lumbar MRI and discography.Methods: We conducted an electronic search of the PubMed, MEDLINE, Embase, and ScienceDirect databases from their respective inceptions to October 2016 using the following search terms: "low back pain," "discogenic low back pain," " HIZ or high-intensity zone," and "discography". Relevant journals and conference proceedings were manually searched. Two reviewers independently assessed the quality of the studies, extracted data from the included studies, and analyzed the data.Results: Eleven studies were included. The results of the meta-analysis indicated that outstanding relativity and statistically significant correlations were observed between the HIZ and abnormal disc morphology (OR = 47.79; 95% CI: 17.07 to 133.77; P < 0.00001), HIZ and pain reproduction (OR = 8.65, 95% CI: 6.01 to 15.23, P < 0.00001), and HIZ and abnormal morphology pain reproduction (OR = 11.74, 95% CI: 1.99 to 69.36, P = 0.007).Conclusions: The presence of an HIZ on a lumbar MRI T2-weighted image indicates abnormal disc morphology. There is a strong relationship between the HIZ and pain reproduction. The HIZ can be an effective index for prediction of discogenic low back pain.