Recent skin self-examination and doctor visits in relation to melanoma risk and tumour depth.
Recent skin self-examination and doctor visits in relation to melanoma risk and tumour depth.
复制标题
最近进行的皮肤自我检查和就诊与黑色素瘤风险和肿瘤深度有关。
DOI：
10.1111/bjd.12003
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Ernstoff,MS
中科院分区：
文献类型：
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作者：
Titus,LJ;Clough-Gorr,K;Mackenzie,TA;Perry,A;Spencer,SK;Weiss,J;Abrahams-Gessel,S;Ernstoff,MS
BackgroundLittle is known about the potential benefit of skin self‐examination for melanoma prevention and early detection.ObjectivesTo determine whether skin self‐examination is associated with reduced melanoma risk, self‐detection of tumours, and reduced risk of deeper melanomas.MethodsWe used data from a population‐based case–control study (423 cases, 678 controls) to assess recent skin self‐examination in relation to self‐detection, melanoma risk and tumour depth ( ≤1 mm; > 1 mm). Logistic regression was used to estimate odds ratios (ORs) and confidence intervals (CIs) for associations of interest.ResultsSkin self‐examination conducted 1–11 times during a recent year was associated with a possible decrease in melanoma risk (OR 0·74; 95% CI 0·54–1·02). Melanoma risk was decreased for those who conducted skin self‐examination and saw a doctor (OR 0·52; 95% CI 0·30–0·90). Among cases, those who examined their skin were twice as likely to self‐detect the melanoma (OR 2·23; 95% CI 1·47–3·38), but self‐detection was not associated with shallower tumours. Tumour depth was reduced for those who conducted skin self‐examination 1–11 times during a recent year (OR 0·39; 95% CI 0·18–0·81), but was not influenced by seeing a doctor, or by conducting skin self‐examination and seeing a doctor.ConclusionsRisk of a deeper tumour and possibly risk of melanoma were reduced by skin self‐examination 1–11 times annually. Melanoma risk was markedly reduced by skin self‐examination coupled with a doctor visit. We cannot, however, exclude the possibility that our findings reflect bias or confounding. Additional studies are needed to elucidate the potential benefits of skin self‐examination for melanoma prevention and early detection.
