Efficient Optimization of Partition Scan Statistics via the Consecutive Partitions Property
Efficient Optimization of Partition Scan Statistics via the Consecutive Partitions Property
复制标题
通过连续分区属性有效优化分区扫描统计
DOI:
10.1080/10618600.2022.2077351
复制
发表时间:
2022
影响因子:
2.4
通讯作者:
Neill, Daniel B.
中科院分区:
文献类型:
--
作者:
Pehlivanian, Charles A.;Neill, Daniel B.
We generalize the spatial and subset scan statistics from the single to the multiple subset case. The two main approaches to defining the log-likelihood ratio statistic in the single subset case—the population-based and expectation-based scan statistics—are considered, leading to risk partitioning and multiple cluster detection scan statistics, respectively. We show that, for distributions in a separable exponential family, the risk partitioning scan statistic can be expressed as a scaledf-divergence of the normalized count and baseline vectors, and the multiple cluster detection scan statistic as a sum of scaled Bregman divergences. In either case, however, maximization of the scan statistic by exhaustive search over all partitionings of the data requires exponential time. To make this optimization computationally feasible, we prove sufficient conditions under which the optimal partitioning is guaranteed to be consecutive. This Consecutive Partitions Property generalizes the linear-time subset scanning property from two partitions (the detected subset and the remaining data elements) to the multiple partition case. While the number of consecutive partitionings ofnelements intotpartitions scales as, making it computationally expensive for larget, we present a dynamic programming approach which identifies the optimal consecutive partitioning intime, thus allowing for the exact and efficient solution of large-scale risk partitioning and multiple cluster detection problems. Finally, we demonstrate the detection performance and practical utility of partition scan statistics using simulated and real-world data. Supplementary materials for this article are available online.
DOI:
--
发表时间:
1965
期刊:
影响因子:
--
作者:
J. Naus
通讯作者:
J. Naus
影响因子:
1.1
作者:
Zhang, Zhenkui;Assuncao, Renato;Kulldorff, Martin
通讯作者:
Kulldorff, Martin