Trends in antimicrobial prescribing rates for children and adolescents
Trends in antimicrobial prescribing rates for children and adolescents
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DOI：
10.1001/jama.287.23.3096
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发表时间：
2002-06-19
影响因子：
120.7
通讯作者：
Hughes, JM
中科院分区：
文献类型：
--
作者：
McCaig, LF;Besser, RE;Hughes, JM
从1980年到1992年，诊所医生为儿童开抗菌药物处方的年比率有所增加。在20世纪90年代，许多生物体的抗菌素耐药性增加，这与抗菌素的使用有关。为了对抗抗生素耐药性的发展，专业和公共卫生组织进行了努力，以促进适当的抗菌药物prescription.Objective抗菌药物处方率的变化进行评估的整体和呼吸道感染的儿童和青少年年龄小于15岁。2500至3500名诊所医生提供的全国门诊医疗调查数据，从1989年至2010年的2年间，6500至13600名儿科就诊者。1990年至1999- 2000年主要结果测量基于人群和就诊的抗菌药物总体处方率和呼吸道感染处方率（中耳炎，咽炎，支气管炎，鼻窦炎，和上呼吸道感染）的儿童和青少年年龄小于15岁。结果平均人口-每1000名15岁以下儿童和青少年的抗菌药物总处方率从838（95%置信区间[CI]，711-966）至1999-2000年的503（95% CI，419-588）（斜率P
Context Annual rates of antimicrobial prescribing for children by office-based physicians increased from 1980 through 1992. The development of antimicrobial resistance, which increased for many organisms during the 1990s, is associated with antimicrobial use. To combat development of antimicrobial resistance, professional and public health organizations undertook efforts to promote appropriate antimicrobial prescribing.Objective To assess changes in antimicrobial prescribing rates overall and for respiratory tract infections for children and adolescents younger than 15 years.Design, Setting, and Participants National Ambulatory Medical Care Survey data provided by 2500 to 3500 office-based physicians for 6500 to 13 600 pediatric visits during 2-year periods from 1989-1990 through 1999-2000.Main Outcome Measures Population- and visit-based antimicrobial prescribing rates overall and for respiratory tract infections (otitis media, pharyngitis, bronchitis, sinusitis, and upper respiratory tract infection) among children and adolescents younger than 15 years.Results The average population-based annual rate of overall antimicrobial prescriptions per 1000 children and adolescents younger than 15 years decreased from 838 (95% confidence interval [CI], 711-966) in 1989-1990 to 503 (95% CI, 419-588) in 1999-2000 (P for slope