Frequency of myasthenia gravis in multiple sclerosis: Report of five cases from Isfahan, Iran
Frequency of myasthenia gravis in multiple sclerosis: Report of five cases from Isfahan, Iran
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DOI：
10.4103/0028-3886.57817
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发表时间：
2009-09-01
期刊：
影响因子：
2.7
通讯作者：
Zarghami, Neda
中科院分区：
文献类型：
--
作者：
Basiri, Keivan;Etemadifar, Masoud;Zarghami, Neda
本研究的目的是确定重症肌无力（MG）的频率和临床特征，在一个大型队列的波斯患者多发性硬化症（MS）生活在伊斯法罕省。我们回顾了在伊斯法罕MS协会（IMSS）登记的确诊MS（McDonalds标准）患者相关MG的病例记录。在登记的1，718名MS患者中，发现6名患者同时患有MS和MG。排除1例数据不足的患者后，患病率为291/100，000（0.29），高于早期报告的患病率。这些结果可能支持MS和MG共享一些共同的免疫发病机制的假设。
This study was designed to determine the frequency and clinical characteristics of myasthenia gravis (MG) in a large cohort of Persian patients with multiple sclerosis (MS) living in the province of Isfahan. We reviewed the case records of patients with definite MS (McDonalds criteria) registered in the Isfahan MS Society (IMSS) for associated MG. Of the 1,718 patients with MS in the registry, six patients were found to have both MS and MG. The prevalence after excluding one patient with insufficient data, was 291 per 100,000 (0.29), a higher prevalence than the earlier reports. These results may support the hypothesis that MS and MG share some common immunopathogenic mechanisms.