A GENETIC-LINKAGE MAP OF THE MOUSE - CURRENT APPLICATIONS AND FUTURE-PROSPECTS
A GENETIC-LINKAGE MAP OF THE MOUSE - CURRENT APPLICATIONS AND FUTURE-PROSPECTS
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DOI：
10.1126/science.8211130
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发表时间：
1993-10-01
期刊：
影响因子：
56.9
通讯作者：
LANDER, ES
中科院分区：
文献类型：
--
作者：
COPELAND, NG;JENKINS, NA;LANDER, ES
技术的进步使得为小鼠绘制高分辨率遗传连锁图成为可能。这些图谱反过来又为通过比较作图了解哺乳动物基因组进化、开发人类疾病的小鼠模型以及鉴定生物体中所有基因的功能提供了令人兴奋的前景。
Technological advances have made possible the development of high-resolution genetic linkage maps for the mouse. These maps in turn offer exciting prospects for understanding mammalian genome evolution through comparative mapping, for developing mouse models of human disease, and for identifying the function of all genes in the organism.