Population genetics of 19 Y-STR loci in Yanbian Korean samples from China
Population genetics of 19 Y-STR loci in Yanbian Korean samples from China
复制标题
中国延边朝鲜族样本中19个Y-STR位点的群体遗传学
DOI：
10.1111/ahg.12296
复制
发表时间：
2019
影响因子：
1.9
通讯作者：
Wang Bao Jie
中科院分区：
文献类型：
--
作者：
Xuan Jin Feng;Adnan Atif;Khan Rehan Ali;Xing Jia Xin;Yao Jun;Wang Bao Jie
背景中国有包括朝鲜族在内的56个民族，2010年人口普查时人口规模约为192万。朝鲜族主要居住在东北地区，包括吉林（59.64%）、黑龙江（20.21%）和辽宁（12.55%）等省，其余分布在中国其他地区。方法采用Goldeneye 20 Y扩增试剂盒，对吉林省252名朝鲜族男性个体的20个Y染色体短串联重复序列（Y-STR）基因座的遗传特征进行了研究。此外，系统发育分析之间的韩国人口和其他相关人群的基础上Y-STR haplotypes.ResultsWe发现了237个不同的单倍型之间的252无关的个体。单倍型频率在0.0238 ~ 0.0040之间，基因多样性在0.9666（DYS 385 a/B）~ 0.2260（DYS 391）之间。随机匹配概率为0.0048，单倍型多样性为0.9992 ± 0.0006，辨别力为0.9405。人群比较显示，朝鲜族人群与东亚其他朝鲜族人群的Y-STR基因座分布趋势一致。结论延边朝鲜族20个Y-STR基因座具有法医学和人类遗传学应用价值。延边朝鲜族与其他来自中国和朝鲜的朝鲜族人群一致，但与其他东亚人群存在显著差异。
BackgroundChina harbors 56 ethnic groups, including Korean, with a population size of approximately 1.92 million at the 2010 census. Most of the Koreans live in Northeastern parts of China, including Jilin (59.64%), Heilongjiang (20.21%), and Liaoning (12.55%) provinces, and the rest are spread to other parts of China. Koreans across China share a common culture, which is similar to Korea.MethodsWe have explored the genetic characteristics of 20 Y‐chromosomal short tandem repeat (Y‐STR) loci in 252 unrelated Chinese Korean male individuals from Jilin Province, using a Goldeneye 20Y amplification kit. Moreover, phylogenetic analysis was performed between the Korean population and other relevant populations based on the Y‐STR haplotypes.ResultsWe have found 237 different haplotypes among 252 unrelated individuals. The haplotype frequencies ranged from 0.0238 to 0.0040, while gene diversity ranged from 0.9666 (DYS385a/b) to 0.2260 (DYS391). The random match probability was 0.0048, the haplotype diversity was 0.9992 ± 0.0006 and discrimination capacity was 0.9405. Population comparison revealed that Korean populations are lining up together with other Korean populations from East Asia.ConclusionOur results showed that the 20 Y‐STR loci in the Yanbian Korean population are valuable for forensic application and human genetics. The Yanbian Koreans have lined up with other Korean population from China and Korea while showing significant differences from other East Asian populations.